1-Epi Gemcitabine Hydrochloride
| Product Name | 1-Epi Gemcitabine Hydrochloride |
|---|---|
| Alternate Names | Gemcitabine Impurities, Impurities of Gemcitabine |
| CAT No. | CS-T-54079 |
| CAS No. | 122111-05-1 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 299.66 g/mol |
| Mol. For. | C₉H₁₂ClF₂N₃O₄ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Gemcitabine |
| Therapeutic | Immunosuppressants |
| Smileys | C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F.Cl |
| Canonical Smiles | C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F.Cl |
| InchIKey | OKKDEIYWILRZIA-DNSZWREKSA-N |
| Inchl | InChI=1S/C9H11F2N3O4.ClH/c10-9(11)6(16)4(3-15)18-7(9)14-2-1-5(12)13-8(14)17;/h1-2,4,6-7,15-16H,3H2,(H2,12,13,17);1H/t4-,6+,7+;/m1./s1 |
| IUPAC | 4-amino-1-[(2S,4S,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one;hydrochloride |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
1-Epi Gemcitabine Hydrochloride is a chemical compound used in the treatment and management of various types of cancer. It is a derivative of the chemotherapy drug Gemcitabine and is commonly used in combination with other chemotherapy drugs to enhance their effectiveness. The chemical structure of 1-Epi Gemcitabine Hydrochloride is similar to that of Gemcitabine, but it differs in that it contains an additional epimeric hydroxyl group. This modification enhances the drug's pharmacological properties by increasing its solubility, bioavailability, and potency.
The mechanism of action of 1-Epi Gemcitabine Hydrochloride involves the inhibition of DNA synthesis and repair, which leads to the death of cancer cells. It also has immunomodulatory effects that help to enhance the immune system's ability to fight cancer. The drug is administered intravenously, and its dosage is determined by the patient's weight, medical history, and response to treatment.
Like other chemotherapy drugs, 1-Epi Gemcitabine Hydrochloride can cause various side effects, including nausea, vomiting, diarrhea, fatigue, hair loss, and decreased blood cell counts. These side effects can be managed with supportive care and medication.
In conclusion, 1-Epi Gemcitabine Hydrochloride is an important chemotherapy drug used in the treatment of cancer. Its unique chemical structure and mechanism of action make it a potent and effective anticancer agent. While it may cause side effects, the benefits of using it in the management of cancer outweigh the risks.
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Related Compounds
Ethyl (3R,S)-2,2-difluoro-3-hydroxy3-(2,2-dimethyldioxolan-4-yl)propionate | Gemcitabine Diphosphate Choline | N-Carboxybenzyl Gemcitabine | Gemcitabine Monophosphate Formate Salt | Gemcitabine 5'-diphosphate | Gemcitabine 5'-elaidate | Gemcitabine 3- benzoate impurity | Gemcitabine Impurity 19 | Gemcitabine Impurity 4 | Gemcitabine α-Anomer | Gemcitabine Alpha Isomer 3 Benzoate | Gemcitabine Alpha Isomer 5 Benzoate |