17-β-Estradiol-d3-β-D-Glucuronide

Product Name 17-β-Estradiol-d3-β-D-Glucuronide
Alternate Names Estradiol Stable Isotopes, Stable Isotopes of Estradiol
CAT No. CS-T-54240
CAS No. 1260231-06-8
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Estradiol
Smileys C[C@@]1([C@@]2([2H])O)[C@](CC2([2H])[2H])([H])[C@@](CCC3=CC(O[C@@H]([C@@H]([C@@H](O)[C@@H]4O)O)O[C@@H]4C(O)=O)=CC=C53)([H])[C@]5([H])CC1
Canonical Smiles CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)OC5C(C(C(C(O5)C(=O)O)O)O)O
InchIKey MUOHJTRCBBDUOW-NCKPPFHHSA-N
Inchl InChI=1S/C24H32O8/c1-24-9-8-14-13-5-3-12(10-11(13)2-4-15(14)16(24)6-7-17(24)25)31-23-20(28)18(26)19(27)21(32-23)22(29)30/h3,5,10,14-21,23,25-28H,2,4,6-9H2,1H3,(H,29,30)/t14-,15-,16+,17+,18+,19+,20-,21+,23-,24+/m1/s1/i7D2,17D
IUPAC (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[[(8R,9S,13S,14S,17S)-16,16,17-trideuterio-17-hydroxy-13-methyl-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-3-yl]oxy]oxane-2-carboxylic acid
Controlled No
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17-β-Estradiol-d3-β-D-Glucuronide, also known as E2G, is a synthetic form of estrogen that is used in various research studies related to hormone metabolism and endocrine function. This compound is a stable isotope-labeled derivative of 17-β-Estradiol, containing three deuterium atoms at specific positions in the molecule. E2G is primarily used as a reference standard for quantifying endogenous levels of estrogen glucuronides in biological samples such as urine, plasma, and serum. It is also used in studies investigating the metabolism and excretion of estrogen metabolites, as well as the roles of glucuronidation in estrogen homeostasis and estrogen-related diseases. The chemical structure of E2G consists of a β-D-glucuronic acid moiety attached to the hydroxyl group at position 17 of the estrogen molecule. The glucuronidation of estrogens is a major pathway of estrogen metabolism, which facilitates their elimination from the body. E2G is stable under normal storage and handling conditions and can be easily synthesized from 17-β-Estradiol-d3 and glucuronic acid. In summary, 17-β-Estradiol-d3-β-D-Glucuronide is a valuable tool for researchers studying estrogen metabolism and hormone-related diseases. Its stable isotope labeling and chemical properties make it an ideal reference standard for accurate quantification of endogenous estrogen glucuronides in biological samples.

Related Compounds

Ethinylestradiol sulfate-D4 | Ethinylestradiol -D4 | Estradiol 17-Valerate-d9 | Estradiol-13C6 | Estradiol 17-Palmitate-d31 | Ethynyl Estradiol-2,4,9,6,6,16,16- D7 | Estradiol D4 | Sodium 17 β-Estradiol 3-Sulfate D4 | Ethynyl Estradiol-13C2 | Estradiol Sulphate D4 sodium |

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