Fexofenadine-d10 Hydrochloride

Product Name Fexofenadine-d10 Hydrochloride
Alternate Names Fexofenadine Stable Isotopes, Stable Isotopes of Fexofenadine
CAT No. CS-T-54704
CAS No. 1215821-44-5
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 548.18 g/mol
Mol. For. C₃₂H₃₀D₁₀ClNO₄
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Fexofenadine
Purity Not specified
Therapeutic Antihistamine
Smileys O=C(O)C(C)(C)C1=CC=C(C(O)CCCN2CCC(C(C3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])(O)C4=C([2H])C([2H])=C([2H])C([2H])=C4[2H])CC2)C=C1.[H]Cl
Canonical Smiles CC(C)(C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O)C(=O)O.Cl
InchIKey RRJFVPUCXDGFJB-MQHVTZQPSA-N
Inchl InChI=1S/C32H39NO4.ClH/c1-31(2,30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(37,26-10-5-3-6-11-26)27-12-7-4-8-13-27;/h3-8,10-13,15-18,28-29,34,37H,9,14,19-23H2,1-2H3,(H,35,36);1H/i3D,4D,5D,6D,7D,8D,10D,11D,12D,13D;
IUPAC 2-[4-[1-hydroxy-4-[4-[hydroxy-bis(2,3,4,5,6-pentadeuteriophenyl)methyl]piperidin-1-yl]butyl]phenyl]-2-methylpropanoic acid;hydrochloride
Controlled No
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Fexofenadine-d10 Hydrochloride is a deuterated form of Fexofenadine Hydrochloride, which is a second-generation antihistamine used to treat allergies, hay fever, and other respiratory allergies. The deuterated form is used for pharmacokinetic studies, drug metabolism research, and clinical trials. Fexofenadine-d10 Hydrochloride is a white to off-white crystalline powder that is freely soluble in water and ethanol. It is a selective antagonist of histamine H1 receptors and does not cross the blood-brain barrier, which means it does not cause drowsiness or sedation. This makes it an effective treatment for allergies without affecting cognitive functions. The chemical formula of Fexofenadine-d10 Hydrochloride is C32H40D10ClN5O4 and its molecular weight is 564.20 g/mol. The deuterated form is produced by replacing ten hydrogen atoms with deuterium atoms at specific positions in the molecule. The recommended dose of Fexofenadine-d10 Hydrochloride is 60mg twice daily or 180mg once daily, depending on the severity of the allergy symptoms. The drug is metabolized in the liver and excreted in the urine, with a half-life of 14.4 hours. In conclusion, Fexofenadine-d10 Hydrochloride is a deuterated form of Fexofenadine Hydrochloride, used for pharmacokinetic studies, drug metabolism research, and clinical trials. It is a selective antagonist of histamine H1 receptors and does not cause drowsiness or sedation, making it an effective treatment for allergies.

Related Compounds

Fexofenadine hydrochloride 13C12 | Fexofenadine-d10 | Fexofenadine-D6 Methyl Ester | Fexofenadine D6 | Fexofenadine-d10 Methyl Ester | Fexofenadine-D6 hydrochloride |

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