3-Hydroxyacetaminophen D3

3-Hydroxyacetaminophen D3 is a deuterated analogue of 3-hydroxyacetaminophen, an active metabolite of acetaminophen (also known as paracetamol). Acetaminophen is a widely used analgesic and antipyretic medication that works by inhibiting the production of prostaglandins, which are responsible for pain and fever. The metabolism of acetaminophen mainly occurs in the liver, where it is converted into several metabolites, including 3-hydroxyacetaminophen. 3-Hydroxyacetaminophen D3 is commonly used as an internal standard in pharmacokinetic and metabolic studies of acetaminophen. Its deuterated structure allows for the accurate quantification of acetaminophen levels in biological samples using mass spectrometry. Additionally, 3-Hydroxyacetaminophen D3 is used in the development and validation of analytical methods for the detection of acetaminophen and its metabolites. The chemical formula of 3-Hydroxyacetaminophen D3 is C8H9D3NO3, and its molecular weight is 169.22 g/mol. Its melting point is 179-180°C, and it is soluble in water and methanol. The compound is stable under normal conditions and should be stored in a cool and dry place. In conclusion, 3-Hydroxyacetaminophen D3 is an important tool for researchers studying the pharmacokinetics and metabolism of acetaminophen. Its deuterated structure allows for accurate quantification of acetaminophen levels in biological samples, making it a valuable internal standard in analytical methods.