6-Hydroxy-4'-tert-butyldimethylsylyl Raloxifene-d4

Product Name 6-Hydroxy-4'-tert-butyldimethylsylyl Raloxifene-d4
Alternate Names Raloxifene Stable Isotopes, Stable Isotopes of Raloxifene
CAT No. CS-T-55772
CAS No. 1189422-34-1
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Raloxifene
Therapeutic Anti-Cancer / Oncology
Smileys CC(C)(C)[Si](C)(C)OC1=CC=C(C=C1)C2=C(C3=C(S2)C=C(C=C3)O)C(=O)C4=CC=C(C=C4)OCCN5CCCCC5
Canonical Smiles CC(C)(C)[Si](C)(C)OC1=CC=C(C=C1)C2=C(C3=C(S2)C=C(C=C3)O)C(=O)C4=CC=C(C=C4)OCCN5CCCCC5
InchIKey YYSIXGNGLSNJGQ-KFESLDSXSA-N
Inchl InChI=1S/C34H41NO4SSi/c1-34(2,3)41(4,5)39-28-16-11-25(12-17-28)33-31(29-18-13-26(36)23-30(29)40-33)32(37)24-9-14-27(15-10-24)38-22-21-35-19-7-6-8-20-35/h9-18,23,36H,6-8,19-22H2,1-5H3/i21D2,22D2
IUPAC [2-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]-6-hydroxy-1-benzothiophen-3-yl]-[4-(1,1,2,2-tetradeuterio-2-piperidin-1-ylethoxy)phenyl]methanone
Controlled No
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6-Hydroxy-4'-tert-butyldimethylsylyl Raloxifene-d4 is a deuterated analogue of the selective estrogen receptor modulator, Raloxifene. It is primarily used in pharmacokinetic and pharmacodynamic studies to gain a better understanding of the drug's metabolism and mode of action. The incorporation of deuterium into the molecule allows for more accurate measurement and tracking of the drug's behavior in biological systems. Raloxifene, and its deuterated analogue, work by selectively binding to estrogen receptors in certain tissues, such as bone and breast tissue, while avoiding activation in other tissues, such as the uterus. This makes it a valuable tool in the prevention and treatment of osteoporosis and breast cancer. Chemically, 6-Hydroxy-4'-tert-butyldimethylsylyl Raloxifene-d4 has a molecular formula of C30H36D4NO4Si and a molecular weight of 536.79 g/mol. It has a melting point of approximately 170-174°C and is soluble in organic solvents such as methanol and dimethyl sulfoxide. Overall, 6-Hydroxy-4'-tert-butyldimethylsylyl Raloxifene-d4 is a useful compound for researchers studying the pharmacokinetics and pharmacodynamics of Raloxifene, as well as for those investigating the mechanisms of action of selective estrogen receptor modulators in general.

Related Compounds

Raloxifene-d4 6-Glucuronide | Raloxifene-d4 6-β-D-Glucuronide Lithium Salt | Raloxifene-d4 Bismethyl Ether | Raloxifene 4 Glucuronide D4 | Raloxifene D4 | Raloxifene D4 Hydrochloride |

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