4-Hydroxy Phenylbutazone D9

4-Hydroxy Phenylbutazone D9 is a deuterated analog of the nonsteroidal anti-inflammatory drug (NSAID) Phenylbutazone. This derivative is often used in pharmacological research as a reference standard for the detection and quantification of Phenylbutazone in biological samples. Phenylbutazone is commonly prescribed for the treatment of pain, fever, and inflammation in both humans and animals. It works by inhibiting the production of prostaglandins, which are responsible for inflammation and pain. However, Phenylbutazone has been associated with adverse effects such as gastrointestinal ulcers, kidney damage, and bone marrow suppression. The deuterated form of 4-Hydroxy Phenylbutazone D9 is useful in pharmacological research as it can be used as an internal standard in liquid chromatography-mass spectrometry (LC-MS) analysis. This allows for accurate quantification of Phenylbutazone in biological samples such as blood or urine. The chemical structure of 4-Hydroxy Phenylbutazone D9 consists of a phenyl ring, a butyl chain, and a hydroxyl group. The deuterium substitution occurs on the butyl chain, with nine deuterium atoms replacing hydrogen atoms. This modification provides a distinct mass difference from the non-deuterated Phenylbutazone, which allows for reliable quantification during analysis. In conclusion, 4-Hydroxy Phenylbutazone D9 is a useful tool in pharmacological research as a reference standard for detecting and quantifying Phenylbutazone in biological samples. Its chemical structure and deuterium substitution allow for accurate analysis using LC-MS techniques. However, it should be noted that Phenylbutazone use should always be under the supervision of a medical professional due to its potential for adverse effects.