Imatinib (Piperazine)-N4-Oxide

Product Name Imatinib (Piperazine)-N4-Oxide
Alternate Names Imatinib Impurities, Impurities of Imatinib
CAT No. CS-T-56606
CAS No. 571186-91-9
Category Impurities
Stock IN-Stock
Mol. Wt. 509.6 g/mol
Mol. For. C29H31N7O2
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Imatinib
Canonical Smiles CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CC[N+](CC3)(C)[O-])NC4=NC=CC(=N4)C5=CN=CC=C5
InchIKey MSADRWGPCQTOST-UHFFFAOYSA-N
Inchl InChI=1S/C29H31N7O2/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-35-14-16-36(2,38)17-15-35/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)
IUPAC 4-[(4-methyl-4-oxidopiperazin-4-ium-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
Controlled No
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Imatinib (Piperazine)-N1-Oxide is a chemical compound that is commonly used as an anti-cancer medication. It is marketed under the brand name Gleevec and is known for its ability to selectively inhibit the activity of tyrosine kinase enzymes in cancer cells, which can help slow or stop the spread of cancer. Imatinib (Piperazine)-N1-Oxide is commonly prescribed for the treatment of chronic myeloid leukemia, gastrointestinal stromal tumors, and other forms of cancer. As a chemical compound, Imatinib (Piperazine)-N1-Oxide has a molecular weight of 493.6 g/mol and a chemical formula of C29H31N7O2. It is classified as a piperazine derivative and is a white to off-white crystalline powder that is highly soluble in water and methanol. The mechanism of action of Imatinib (Piperazine)-N1-Oxide involves its ability to bind to the ATP-binding site of tyrosine kinase enzymes. By inhibiting the activity of these enzymes, Imatinib (Piperazine)-N1-Oxide can reduce the proliferation and survival of cancer cells. It is also known to induce apoptosis (programmed cell death) in cancer cells, which can help to further reduce the spread of cancer. Overall, Imatinib (Piperazine)-N1-Oxide is an important medication in the fight against cancer. Its ability to target specific enzymes in cancer cells makes it an effective tool in the treatment of many types of cancer, and ongoing research continues to explore its potential in new areas.

Related Compounds

Imatinib Impurity B | Des-4-methylpiperazin chloro Imatinib impurity | Imatinib EP Impurity C Trihydrochloride | Imatinib EP Impurity D Tetrahydrochloride | Imatinib EP Impurity D | Imatinib Impurity 16 | Fluorescent derivative of imatinib | Imatinib Guanidino Dihydrochloride Impurity | N-Nitroso Imatinib impurity F | Imatinib (Pyridine)-N-oxide | N-Nitroso Imatinib guanidine Intermediate | N-Desmethyl -n-nitroso imatinib 1 | Imatinib (N-nitroso benzamide) | Imatinib impurity B | Imatinib Dimer | Imatinib Dimethylamino Impurity | Imatinib N-Desmethyl Impurity | Imatinib Impurity 5 | N-Nitroso Imatinib Nitro Intermediate | Imatinib Hydrochloride Impurity G | N-(3-methyl5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4((4-methylpiperazin-1-yl)methyl)benz | Imatinib EP Impurity C | N-Desmethyl Imatinib Mesylate | N-Desmethyl -N-Nitroso Imatinib | Imatinib EP Impurity D (chloride) | N-Boc-N-Desmethyl Imatinib | Imatinib DiPiperazine Impurity | Imatinib Impurity 3 | Imatinib Imidazole Impurity | N-(2-Methyl-5-nitrophenyl)-4-(pyridine-3-yl)pyridine-2-amine | Imatinib N-Formyl Impurity | N-Nitroso Imatinib | Imatinib N-Acetyl Impurity |

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