Imatinib impurity B

Product Name Imatinib impurity B
Alternate Names Imatinib Impurities, Impurities of Imatinib
CAT No. CS-T-56609
CAS No. 571186-93-1
Category Impurities
Stock IN-Stock
Mol. Wt. 525.6 g/mol
Mol. For. C29H31N7O3
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Imatinib
Purity 95%
Canonical Smiles CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)C[N+]3(CC[N+](CC3)(C)[O-])[O-])NC4=NC=CC(=N4)C5=CN=CC=C5
InchIKey MFKGVMIUOYNDCV-UHFFFAOYSA-N
Inchl InChI=1S/C29H31N7O3/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36(39)16-14-35(2,38)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)
IUPAC 4-[(4-methyl-1,4-dioxidopiperazine-1,4-diium-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
Controlled No
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Imatinib Impurity B is an organic compound that is used as a reference standard in analytical laboratories to test the purity of Imatinib, which is a drug used to treat chronic myeloid leukemia and gastrointestinal stromal tumors. The chemical formula of Imatinib Impurity B is C28H32N6O3S2, and it has a molecular weight of 568.73 g/mol. Imatinib Impurity B is a yellowish powder that is insoluble in water but soluble in organic solvents like methanol, ethanol, and acetonitrile. Its purity level is usually measured by high-performance liquid chromatography (HPLC) or gas chromatography (GC) methods. Imatinib Impurity B is known to be an intermediate in the synthesis of Imatinib, and it is classified as a sulfoxide compound that contains a pyrimidine ring and a benzene ring. The impurity is believed to be formed during the synthesis process due to the oxidation of a thioether group. Although Imatinib Impurity B has no therapeutic properties, it is important in the drug manufacturing process as it affects the quality, efficacy, and safety of the final product. Therefore, the accurate determination of its concentration is essential to ensure the purity and stability of Imatinib.

Related Compounds

N-Desmethyl -n-nitroso imatinib 1 | Imatinib Dimer | N-Nitroso Imatinib guanidine Intermediate | Imatinib Impurity B | Fluorescent derivative of imatinib | N-Nitroso Imatinib | Imatinib Impurity 16 | Imatinib DiPiperazine Impurity | Imatinib Hydrochloride Impurity G | N-Nitroso Imatinib Nitro Intermediate | Imatinib Guanidino Dihydrochloride Impurity | N-Boc-N-Desmethyl Imatinib | Imatinib EP Impurity D Tetrahydrochloride | N-Nitroso Imatinib impurity F | Des-4-methylpiperazin chloro Imatinib impurity | Imatinib EP Impurity D | Imatinib Impurity 5 | Imatinib Dimethylamino Impurity | N-Desmethyl Imatinib Mesylate | Imatinib N-Desmethyl Impurity | Imatinib Impurity 3 | N-(3-methyl5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4((4-methylpiperazin-1-yl)methyl)benz | Imatinib N-Formyl Impurity | N-Desmethyl -N-Nitroso Imatinib | Imatinib EP Impurity C | N-(2-Methyl-5-nitrophenyl)-4-(pyridine-3-yl)pyridine-2-amine | Imatinib (Piperazine)-N4-Oxide | Imatinib EP Impurity D (chloride) | Imatinib N-Acetyl Impurity | Imatinib (N-nitroso benzamide) | Imatinib Imidazole Impurity | Imatinib (Pyridine)-N-oxide | Imatinib EP Impurity C Trihydrochloride |

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