Isosorbide 13C6 5-Mononitrate

Product Name Isosorbide 13C6 5-Mononitrate
CAT No. CS-T-56916
CAS No. 1217604-00-6
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 197.09 g/mol
Mol. For. ¹³C₆H₉NO₆
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Smileys O=[N](O[13C@H]1[13C@](O[13CH2][13C@@H]2O)([H])[13C@]2([H])O[13CH2]1)=O
Canonical Smiles C1C(C2C(O1)C(CO2)O[N+](=O)[O-])O
InchIKey YWXYYJSYQOXTPL-AEKYUDOOSA-N
Inchl InChI=1S/C6H9NO6/c8-3-1-11-6-4(13-7(9)10)2-12-5(3)6/h3-6,8H,1-2H2/t3-,4+,5+,6+/m0/s1/i1+1,2+1,3+1,4+1,5+1,6+1
IUPAC [(3S,3aR,6R,6aS)-3-hydroxy-2,3,3a,5,6,6a-hexahydro(2,3,4,5-13C4)furano[3,2-b](2,3,4,5-13C4)furan-6-yl] nitrate
Controlled No
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Isosorbide 13C6 5-Mononitrate is a chemical compound that is used to treat angina pectoris, a condition characterized by chest pain caused by reduced blood flow to the heart. This compound is a type of nitrate that works by dilating the blood vessels, thereby increasing blood flow and oxygen supply to the heart. Isosorbide 13C6 5-Mononitrate is typically administered orally in tablet form. Chemically, Isosorbide 13C6 5-Mononitrate is a nitrate ester of isosorbide, a six-carbon sugar alcohol. The compound is labeled with six carbon-13 isotopes, which can be used for isotope tracing studies. Isotope tracing studies are used to identify metabolic pathways and to determine the fate of molecules in biological systems. Isosorbide 13C6 5-Mononitrate is metabolized in the liver to its active form, 5-nitrate, which is responsible for its therapeutic effects. The compound has a half-life of approximately five hours and is primarily eliminated through the kidneys. Like other nitrate compounds, Isosorbide 13C6 5-Mononitrate can cause side effects such as headache, dizziness, and flushing due to its vasodilatory effects. It is important to follow the prescribed dosage and to avoid alcohol consumption while taking this medication. Isosorbide 13C6 5-Mononitrate should also not be used together with certain medications, such as sildenafil (Viagra), as it can cause a dangerous drop in blood pressure.

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