Ivermectin B1 Aglycon

Product Name Ivermectin B1 Aglycon
Alternate Names Ivermectin Impurities, Impurities of Ivermectin
CAT No. CS-T-56936
CAS No. 73162-95-5
Category Impurities
Stock IN-Stock
Mol. Wt. 586.76 g/mol
Mol. For. C₃₄H₅₀O₈
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Ivermectin
Canonical Smiles CCC(C)C1C(CCC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)O)C)C
InchIKey XOCXXEYUGYTCNG-AFVSOJIRSA-N
Inchl InChI=1S/C34H50O8/c1-7-19(2)30-22(5)13-14-33(42-30)17-26-16-25(41-33)12-11-21(4)28(35)20(3)9-8-10-24-18-39-31-29(36)23(6)15-27(32(37)40-26)34(24,31)38/h8-11,15,19-20,22,25-31,35-36,38H,7,12-14,16-18H2,1-6H3/b9-8-,21-11-,24-10?/t19-,20-,22-,25+,26-,27-,28-,29+,30+,31+,33+,34+/m0/s1
IUPAC (1R,4S,5'S,6R,6'R,8R,10Z,12S,13S,14Z,20R,21R,24S)-6'-[(2S)-butan-2-yl]-12,21,24-trihydroxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one
Controlled No
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Ivermectin B1 Aglycon is a chemical compound that belongs to the class of macrocyclic lactones. It is a derivative of avermectin, which is produced by the soil-dwelling bacterium Streptomyces avermitilis. Ivermectin B1 Aglycon is widely used in veterinary medicine as an anthelmintic agent to control and treat parasitic infections in livestock, including nematodes, mites, and lice. It has also been used to treat parasitic infections in humans, including river blindness and certain types of roundworm infections. Ivermectin B1 Aglycon works by targeting the nervous system of parasites and causing paralysis and death. It binds to glutamate-gated chloride channels in the parasite's nerve and muscle cells, which results in hyperpolarization of the cell membrane and inhibition of nerve impulses. This leads to muscle paralysis and death of the parasite. Ivermectin B1 Aglycon has a low toxicity profile, making it safe for use in animals and humans. However, it can have some side effects, including gastrointestinal disturbances, dizziness, and skin rash. It should be used with caution in pregnant and lactating animals and humans. In conclusion, Ivermectin B1 Aglycon is a potent anthelmintic agent that is widely used in veterinary medicine to treat parasitic infections in livestock. Its low toxicity profile and effectiveness against a wide range of parasites make it a valuable tool in the fight against parasitic infections.

Related Compounds

Ivermectin aglycone | Ivermectin EP Impurity J | Ivermectin EP Impurity F | Ivermectin B1 Mono-sugar Derivative | Desmethyl IVERMECTIN B1A | Ivermectin 8a-oxo-H2B1a | Ivermectin Impurity 1 | Ivermectin EP Impurity E | Ivermectin EP Impurity C | rac-2,3-Dehydro-3,4-dihydro Ivermectin | Ivermectin(Secondary Standards traceble to USP) | Ivermectin Photolytic degradation impurity-2 (aldehyde impurity) |

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