Loratadine-d5 (ethyl-d5)
| Product Name | Loratadine-d5 (ethyl-d5) |
|---|---|
| CAT No. | CS-T-57296 |
| CAS No. | 1398065-63-8 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 387.91 g/mol |
| Mol. For. | C22H18D5ClN2O2 |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Therapeutic | Antihistamine |
| Smileys | ClC1=CC=C2C(CCC3=CC=CN=C3/C2=C4CCN(C(OC([2H])([2H])C([2H])([2H])[2H])=O)CC\4)=C1 |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Loratadine D5 is a deuterated version of the antihistamine drug Loratadine, which is primarily used to treat allergic reactions such as hay fever, hives, and other related conditions. Loratadine D5 is a white crystalline powder that is soluble in water and has a molecular weight of 407.55 g/mol. It is a selective antagonist of the H1 histamine receptor, which means that it binds to the receptor and inhibits the action of histamine, which is responsible for causing allergic reactions.
One of the main advantages of using Loratadine D5 over Loratadine is that it is isotopically labeled with five deuterium atoms, which can be used in pharmacokinetic studies to determine the metabolic fate of the drug in the body. This labeling also allows for more accurate and sensitive detection of the drug in biological samples, which is useful in clinical trials and other research studies.
Loratadine D5 is typically administered orally in the form of tablets or syrup, and the recommended dosage is usually 10 mg once per day. The drug is metabolized in the liver and excreted primarily in the urine, with a half-life of approximately 8-14 hours.
Overall, Loratadine D5 is a useful tool for studying the pharmacokinetics and metabolism of Loratadine, and it offers several advantages over the non-deuterated form of the drug.
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