1-Methoxy-2,3,5-trimethylbenzene-d3

1-Methoxy-2,3,5-trimethylbenzene-d3, also known as anisole-d3, is a deuterated derivative of anisole. It is commonly used as an internal standard in various analytical techniques, including nuclear magnetic resonance (NMR) spectroscopy, gas chromatography-mass spectrometry (GC-MS), and liquid chromatography-mass spectrometry (LC-MS). The deuterium-labeled compound is preferred as an internal standard because it provides a clear and distinct signal that does not overlap with other signals in a sample, thus allowing for accurate quantification of the target compound. Additionally, the use of deuterated internal standards improves the precision and accuracy of the analytical results, as it reduces errors caused by matrix effects and sample preparation. From a chemical perspective, anisole-d3 is a colorless liquid with a molecular formula of C9H9DO. It has a boiling point of 155-157°C, a melting point of -36°C, and a density of 0.95 g/cm3. The compound is relatively stable under normal conditions, but may react with strong oxidizing agents or acids. In summary, 1-Methoxy-2,3,5-trimethylbenzene-d3 is a useful internal standard in analytical chemistry that provides accurate and precise results in various techniques. Its chemical properties make it a stable and reliable compound for laboratory use.