(S)-(-)-Nicotine-d4

Product Name (S)-(-)-Nicotine-d4
Alternate Names Nicotine Stable Isotopes, Stable Isotopes of Nicotine
CAT No. CS-T-59262
CAS No. 284685-07-0
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Nicotine
Smileys CN1CCCC1C2=CN=CC=C2
Canonical Smiles CN1CCCC1C2=CN=CC=C2
InchIKey SNICXCGAKADSCV-VJPMMSBNSA-N
Inchl InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1/i2D,4D,6D,8D
IUPAC 2,3,4,6-tetradeuterio-5-[(2S)-1-methylpyrrolidin-2-yl]pyridine
Controlled No
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(S)-(-)-Nicotine-d4 is a deuterated form of the natural alkaloid nicotine. It is a chiral compound with four deuterium atoms substituted for hydrogen atoms at specific positions. This isotopically labeled compound is used in medical research and drug development studies to understand the pharmacokinetics and metabolism of nicotine. Nicotine is a potent and addictive alkaloid found in tobacco leaves. It acts on nicotinic acetylcholine receptors (nAChRs) in the brain and other parts of the body. The binding of nicotine to nAChRs leads to the release of neurotransmitters such as dopamine, which results in feelings of pleasure and reward. However, nicotine is also associated with various health risks, including addiction, cardiovascular disease, cancer, and respiratory diseases. (S)-(-)-Nicotine-d4, like nicotine, is a weak base and has a pKa of 8.02. It has a molecular weight of 163.27 g/mol and a melting point of -80°C. It is soluble in water, ethanol, and dimethyl sulfoxide (DMSO). In research, (S)-(-)-Nicotine-d4 is used as a reference standard for the analysis of nicotine and its metabolites in biological samples. It helps researchers to accurately quantify nicotine levels in blood, urine, and other tissues. Additionally, the deuterium-labeled compound can be used to study the metabolism of nicotine in humans and animal models.

Related Compounds

Nicotine-D3-β-D-Glucuronide | rac-Nicotine-1,2’,3’,4’,5’,6’-13C6 | S-(-)-NICOTINE-D1-(5)-IMINIUM DIPERCHLORATE SALT | rac-Nicotine 13CD3 | rac-Nicotine-2',3',3'-d3 | rac-Nicotine D4 | N-Formylnornicotine-D4 | N'-Nitrosonornicotine-2,4,5,6-d4(pyridine-d4) | rac-Nicotine 1-Oxide-d4 | Methyl Metanicotine-d3 |

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