N'-Nitro-N-nitroso-N-methylguanidine

N'-Nitro-N-nitroso-N-methylguanidine, commonly known as MNNG, is a carcinogenic and mutagenic compound that is widely used in biomedical research to induce DNA damage and mutations. MNNG is a potent alkylating agent that reacts with DNA bases, resulting in the formation of DNA adducts and cross-links, which can lead to cell death or genetic mutations. In addition to its research applications, MNNG has also been used as a food preservative and as a component in rocket fuel. However, its use in these industries has been largely discontinued due to its health risks and environmental impact. MNNG is highly toxic and can cause severe health effects if ingested, inhaled, or absorbed through the skin. Exposure to MNNG has been linked to an increased risk of cancer, particularly of the liver, lung, and bladder. It can also cause damage to the nervous system and reproductive system. Due to its hazardous properties, the use of MNNG is strictly regulated and requires proper protective equipment and handling procedures. Researchers and industry professionals must follow strict safety protocols when working with this compound to minimize the risk of exposure and prevent environmental contamination.