(R,S)-Nornicotine D4

(R,S)-Nornicotine D4 is an isotopically labeled form of nornicotine, a natural alkaloid found in tobacco plants. It is a chiral compound, meaning it exists in two mirror-image forms, or enantiomers, designated as (R)- and (S)-nornicotine. The (R,S)-nornicotine D4 refers to a mixture of the two enantiomers that have been labeled with four deuterium atoms. The primary use of (R,S)-nornicotine D4 is in scientific research, particularly in pharmacokinetic and metabolic studies related to nicotine and tobacco use. By labeling the compound with deuterium, researchers can track its movement and transformation within the body, providing valuable insights into how nicotine is metabolized and eliminated from the body. Chemically, (R,S)-nornicotine D4 has a molecular formula of C10H10D4N2 and a molecular weight of 184.27 g/mol. It is a colorless to pale yellow liquid that is soluble in water and organic solvents. The compound has a pKa value of 8.64, indicating that it is a weak base. In summary, (R,S)-nornicotine D4 is a labeled form of nornicotine that is primarily used in scientific research. Its isotopic labeling allows for tracking of the compound in the body, providing important information on nicotine metabolism.