Ondansetron-d3

Product Name Ondansetron-d3
Alternate Names Ondansetron Stable Isotopes, Stable Isotopes of Ondansetron
CAT No. CS-T-59947
CAS No. 1132757-82-4
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 296.38 g/mol
Mol. For. C₁₈H₁₆D₃N₃O
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Ondansetron
Purity 95%
Therapeutic Anti-Cancer / Oncology
Smileys O=C(C(CC1)CN2C(C)=NC=C2)C3=C1N(C([2H])([2H])[2H])C4=CC=CC=C34
Canonical Smiles CC1=NC=CN1CC2CCC3=C(C2=O)C4=CC=CC=C4N3C
InchIKey FELGMEQIXOGIFQ-BMSJAHLVSA-N
Inchl InChI=1S/C18H19N3O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2/h3-6,9-10,13H,7-8,11H2,1-2H3/i2D3
IUPAC 3-[(2-methylimidazol-1-yl)methyl]-9-(trideuteriomethyl)-2,3-dihydro-1H-carbazol-4-one
Controlled No
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Ondansetron-d3 is a deuterated form of ondansetron, which is a medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, and surgery. The deuterated form of ondansetron is used in biomedical research and clinical studies to assess the pharmacokinetics and pharmacodynamics of the drug. The chemical formula of ondansetron-d3 is C18H19D3N4O, and its molecular weight is 295.41 g/mol. It is a white to off-white crystalline powder that is soluble in water and ethanol. The deuterium atoms in ondansetron-d3 are stable isotopes of hydrogen, which do not alter the pharmacological activity of the drug. Ondansetron-d3 is usually administered intravenously or orally in a dose of 8 mg, and its effects last for several hours. It acts by blocking the action of serotonin, a neurotransmitter that can trigger nausea and vomiting. Ondansetron-d3 is metabolized in the liver and excreted in the urine and feces. Although ondansetron-d3 is not approved for clinical use, it is an important tool for drug development and research, as it allows for accurate measurement of drug concentrations in biological samples. Its deuterated form provides a unique signature that can be detected by mass spectrometry, which is a powerful analytical technique used to identify and quantify molecules in complex matrices.

Related Compounds

Ondansetron 13CD3 | Ondansetron-d3 Hydrochloride Salt | Ondansetron D6 Hydrochloride |

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