Prucalopride Succinate

Product Name Prucalopride Succinate
Alternate Names Prucalopride Impurities, Impurities of Prucalopride
CAT No. CS-T-60876
CAS No. 179474-85-2
Category Impurities
Stock IN-Stock
Mol. Wt. 485.96 g/mol
Mol. For. C₂₂H₃₂ClN₃O₇
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Prucalopride
Purity 95%
Smileys OC(CCC(O)=O)=O.O=C(C1=CC(Cl)=C(N)C2=C1OCC2)NC3CCN(CCCOC)CC3
Canonical Smiles COCCCN1CCC(CC1)NC(=O)C2=CC(=C(C3=C2OCC3)N)Cl.C(CC(=O)O)C(=O)O
InchIKey QZRSNVSQLGRAID-UHFFFAOYSA-N
Inchl InChI=1S/C18H26ClN3O3.C4H6O4/c1-24-9-2-6-22-7-3-12(4-8-22)21-18(23)14-11-15(19)16(20)13-5-10-25-17(13)14;5-3(6)1-2-4(7)8/h11-12H,2-10,20H2,1H3,(H,21,23);1-2H2,(H,5,6)(H,7,8)
IUPAC 4-amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide;butanedioic acid
Controlled No
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Prucalopride Succinate is a medication used to treat chronic constipation in adults, especially those with irritable bowel syndrome with constipation (IBS-C). It belongs to the class of drugs called selective serotonin subtype 4 (5-HT4) receptor agonists. The chemical formula of Prucalopride Succinate is C18H26N2O2•C4H6O4, and its molecular weight is 448.54 g/mol. It is available in tablet form with strengths of 1 mg and 2 mg, and is usually taken orally once daily. Prucalopride Succinate works by stimulating the 5-HT4 receptors in the gastrointestinal tract, which increases the motility of the colon and accelerates the passage of stool. This helps to relieve chronic constipation and improve bowel movements. The drug is metabolized in the liver and excreted mainly in the feces. It has a half-life of approximately 24 hours, and its effects can be observed within a few days of starting treatment. However, it may take up to 4 weeks for the full benefits of the medication to be realized. Prucalopride Succinate is generally well-tolerated, and the most common side effects reported include headache, nausea, diarrhea, and abdominal pain. It should not be used in patients with a history of bowel obstruction or severe inflammatory bowel disease. Additionally, it should be used with caution in patients with impaired liver function.

Related Compounds

Prucalopride Impurity 4 | Prucalopride Bromo Impurity | PRUCALOPRIDE SUCCINATE IMPURITY 4 | Prucalopride open ring impurity | Prucalopride Impurity 38 | Prucalopride Impurity 28 | Prucalopride Impurity 35 | N-Nitroso Prucalopride Impurity A | Prucalopride Impurity A | Prucalopride Impurity 37 | Desmethyl Prucalopride | Prucalopride Impurity 3 | Prucalopride Impurity 5 | Prucalopride Impurity E | Prucalopride Impurity B | Prucalopride Impurity 7 | Prucalopride Impurity 36 | Prucalopride Impurity 10 | Prucalopride Impurity D | Prucalopride Impurity 31 | Prucalopride 3-Hydroxy Impurity | Prucalopride N-Oxide | Prucalopride Impurity C | Prucalopride dihydroxy n-oxide impurity | Prucalopride Impurity 39 | Prucalopride Impurity 1 | Prucalopride Impurity 32 | Prucalopride Impurity 6 | Prucalopride Lactose Adduct | Prucalopride Hydroxy Impurity | N-nitroso piperidine -4-one impurity | Prucalopride Impurity 9 | Prucalopride Impurity 8 |

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