Bortezomib Impurity B

Product Name Bortezomib Impurity B
Alternate Names Bortezomib Impurities, Impurities of Bortezomib
CAT No. CS-T-60906
CAS No. 114457-94-2
Category Impurities
Stock IN-Stock
Mol. Wt. 271.27 g/mol
Mol. For. C₁₄H₁₃N₃O₃
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Bortezomib
Therapeutic Synthetic Peptides
Smileys C1=CC=C(C=C1)CC(C(=O)O)NC(=O)C2=NC=CN=C2
Canonical Smiles C1=CC=C(C=C1)CC(C(=O)O)NC(=O)C2=NC=CN=C2
InchIKey DWYZPDHMMZGQAP-NSHDSACASA-N
Inchl InChI=1S/C14H13N3O3/c18-13(12-9-15-6-7-16-12)17-11(14(19)20)8-10-4-2-1-3-5-10/h1-7,9,11H,8H2,(H,17,18)(H,19,20)/t11-/m0/s1
IUPAC (2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoic acid
Controlled No
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Bortezomib Impurity B is a chemical compound that is used in research laboratories and pharmaceutical industries. It is also known by its chemical name, 3-[(1R)-1-[[(2S)-2-methyl-4-oxo-1,3-thiazolidin-3-yl]carbonyl]butyl]-1H-indole-2-carboxylic acid. Bortezomib Impurity B is a degradation product of Bortezomib, which is a drug used to treat multiple myeloma and mantle cell lymphoma. Chemically, Bortezomib Impurity B is an indole derivative that contains a thiazolidine-2,4-dione moiety. It is a yellowish-white powder that is soluble in organic solvents such as methanol and acetonitrile. The purity of Bortezomib Impurity B is typically measured by high-performance liquid chromatography (HPLC). In research laboratories, Bortezomib Impurity B is used as a reference standard for the identification and quantification of Bortezomib degradation products. It is also used to study the chemical stability of Bortezomib and to develop analytical methods for the detection of Bortezomib and its impurities. In the pharmaceutical industry, Bortezomib Impurity B is used during the development and manufacturing of Bortezomib to ensure the quality and purity of the final product. It is also used as a reference standard for quality control and batch release testing. Overall, Bortezomib Impurity B is an important chemical compound that plays a critical role in the development and manufacturing of Bortezomib, a drug used to treat multiple myeloma and mantle cell lymphoma.

Related Compounds

Bortezomib Impurity 6 | Bortezomib Impurity 11 | N-[2-[(3-methyl-1-oxobutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-2-Pyrazinecarboxamide | Bortezomib Impurity 10 | Bortezomib Impurity 32 | Bortezomib Impurity H | Pyrazine-2-carboxylic acid [1-(1-hydroxy-3-methyl-butyl carbamoyl)-2-phenyl-ethyl]-amide | Bortezomib Impurity 9 | Bortezomib Desphenylalanyl Analog | Pyrazine-2-carboxylic acid (1-[3-methyl-1-(2,9-dimethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.0.2.6]dec-4-yl)-butylcarbamoyl]-2-phenyl-ethyl)-amide | Bortezomib N-Formyl analog | Bortezomib Impurity G | Bortezomib D-phenylalanyl analog | Bortezomib Impurity F | N-(1-(((R)-1-hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide | Bortezomib Impurity 29 | Bortezomib impurity D | Pyrazine-2-carboxylic acid(1-(3-methyl-butylcarbamoyl)-2-phenyl-ethyl)-amide | Hydroxy Bortezomib | Bortezomib Impurity 55 | Bortezomib Dimer | N-(1-((3-methyl-1-((3aS,4S,6S,7aS)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide | Bortezomib Impurity 3 (S-isomer) | Bortezomib Impurity C | Bortezomib Hydroxy ketone analog |

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