Quinaprilat d5

Product Name Quinaprilat d5
Alternate Names Quinapril Stable Isotopes, Stable Isotopes of Quinapril
CAT No. CS-T-61013
CAS No. 1279034-23-9
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 415.49 g/mol
Mol. For. C₂₃H₂₁D₅N₂O₅
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Quinapril
Purity >98%
Therapeutic Anti-Hypertensives
Smileys O=C(N(CC1=CC=CC=C1C2)[C@@H]2C(O)=O)[C@H](C)N[C@H](C(O)=O)CCC(C([2H])=C3[2H])=C(C([2H])=C3[2H])[2H]
Canonical Smiles CC(C(=O)N1CC2=CC=CC=C2CC1C(=O)O)NC(CCC3=CC=CC=C3)C(=O)O
InchIKey FLSLEGPOVLMJMN-KKQRNKNXSA-N
Inchl InChI=1S/C23H26N2O5/c1-15(24-19(22(27)28)12-11-16-7-3-2-4-8-16)21(26)25-14-18-10-6-5-9-17(18)13-20(25)23(29)30/h2-10,15,19-20,24H,11-14H2,1H3,(H,27,28)(H,29,30)/t15-,19-,20-/m0/s1/i2D,3D,4D,7D,8D
IUPAC (3S)-2-[(2S)-2-[[(1S)-1-carboxy-3-(2,3,4,5,6-pentadeuteriophenyl)propyl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
Controlled No
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Quinaprilat d5 is a deuterated form of the drug Quinaprilat, which is an angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure and heart failure. Quinaprilat d5 is used primarily as a research tool in pharmacokinetic studies, where it is used as a stable isotope-labeled internal standard for the quantification of Quinaprilat in biological samples. Quinaprilat d5 has the same chemical structure as Quinaprilat, with the addition of five deuterium atoms. This modification allows for accurate and precise measurement of Quinaprilat levels in biological samples using mass spectrometry techniques. The deuterium labeling also increases the stability and shelf-life of the compound. Chemically, Quinaprilat d5 is a dipeptide derivative containing a proline residue. It acts by inhibiting the activity of the ACE enzyme, which is involved in the regulation of blood pressure and fluid balance in the body. By inhibiting ACE, Quinaprilat d5 reduces the production of angiotensin II, a hormone that causes blood vessels to constrict, leading to decreased blood pressure and improved cardiac function. Overall, Quinaprilat d5 is a valuable tool for researchers studying the pharmacokinetics and pharmacodynamics of Quinaprilat and other ACE inhibitors, with potential applications in drug development and personalized medicine.

Related Compounds

Quinapril D5 hydrochloride | N-Nitroso Quinapril-d5 | Quinapril D4 | Quinapril D5 |

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