Tenofovir Disoproxil Dimer

Tenofovir Disoproxil Dimer (TDFD) is an antiviral medication used to treat HIV-1 and hepatitis B virus (HBV) infections. TDFD is a prodrug, which means it is converted into its active form, tenofovir diphosphate, after administration. TDFD is administered orally in the form of tablets or capsules. TDFD belongs to a class of antiviral drugs called nucleotide reverse transcriptase inhibitors (NRTIs). It works by blocking the action of an enzyme called reverse transcriptase, which is responsible for copying the genetic material of the virus into the DNA of the host cell. By inhibiting this enzyme, TDFD prevents the virus from replicating and spreading. TDFD is metabolized in the liver and excreted in the urine. It has a half-life of about 17 hours, which means it stays in the body for a relatively long time. TDFD is generally well-tolerated, with few side effects. The most common side effects include nausea, diarrhea, and headache. TDFD is a potent and effective treatment for HIV-1 and HBV infections. It is often used in combination with other antiviral drugs to achieve a complete suppression of the virus. TDFD should only be used under the supervision of a healthcare provider, who can monitor for any adverse effects and adjust the dosage as needed.