[1',2',3',4',5' 13C5]Uridine

[1',2',3',4',5' 13C5]Uridine is a stable isotope-labeled compound that is used extensively in biochemical and molecular biology research. Uridine is a nucleoside, which is an important building block of RNA and DNA. The 13C5-labeled version of uridine is used in a range of applications that require precise measurements of RNA and DNA synthesis, stability, and turnover rates. One of the primary uses of [1',2',3',4',5' 13C5]Uridine is in metabolic labeling experiments. Scientists can introduce this labeled uridine into cells and track its incorporation into newly synthesized RNA molecules. By measuring the rate of incorporation, researchers can gain insights into the regulation of gene expression and the cellular response to various stimuli. Another important application of [1',2',3',4',5' 13C5]Uridine is in studies of RNA editing. RNA editing is a process by which the sequence of an RNA molecule is altered after transcription. By incorporating labeled uridine into RNA molecules, scientists can track the editing process and identify the specific sites of modification. In terms of chemical information, [1',2',3',4',5' 13C5]Uridine has a molecular weight of 267.2 g/mol and a chemical formula of C9H13N2O6. It is a white crystalline powder that is soluble in water and other polar solvents. The labeled carbon atoms are incorporated into the ribose sugar and the pyrimidine base of the uridine molecule, allowing for precise tracking of its metabolic fate in biological systems.