Trifluorothymine-13C,15N2

Trifluorothymine-13C,15N2 is a synthetic nucleoside analogue that is commonly used in the field of medical research. This compound is structurally similar to thymine, one of the four nucleotides that make up DNA. However, the addition of three fluorine atoms to the molecule makes it highly resistant to breakdown by the enzyme thymidine phosphorylase, which is responsible for the metabolism of thymidine. The unique properties of Trifluorothymine-13C,15N2 make it a useful tool for studying DNA replication and repair mechanisms, as well as for the development of new cancer treatments. In particular, researchers have found that the incorporation of Trifluorothymine-13C,15N2 into DNA can lead to the formation of highly mutagenic lesions, which can be used to selectively target cancer cells. Chemically, Trifluorothymine-13C,15N2 is a modified nucleoside that contains two isotopes of nitrogen and one isotope of carbon. Its molecular formula is C10H9F3N2O2, and it has a molecular weight of 266.19 g/mol. The compound is typically synthesized using a combination of organic chemistry techniques, such as nucleophilic substitution and reductive amination. Overall, Trifluorothymine-13C,15N2 is a powerful tool for exploring the complex world of DNA replication and cancer biology. Its unique chemical properties make it a valuable asset for researchers in the field of medical science who are working to develop new treatments for cancer and other diseases.