ABT 263-d8
| Product Name | ABT 263-d8 |
|---|---|
| CAT No. | CS-T-64123 |
| CAS No. | 1217620-38-6 |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Smileys | CC1(CCC(=C(C1)CN2CCN(CC2)C3=CC=C(C=C3)C(=O)NS(=O)(=O)C4=CC(=C(C=C4)NC(CCN5CCOCC5)CSC6=CC=CC=C6)S(=O)(=O)C(F)(F)F)C7=CC=C(C=C7)Cl)C |
| Canonical Smiles | CC1(CCC(=C(C1)CN2CCN(CC2)C3=CC=C(C=C3)C(=O)NS(=O)(=O)C4=CC(=C(C=C4)NC(CCN5CCOCC5)CSC6=CC=CC=C6)S(=O)(=O)C(F)(F)F)C7=CC=C(C=C7)Cl)C |
| InchIKey | JLYAXFNOILIKPP-YSUYZUONSA-N |
| Inchl | InChI=1S/C47H55ClF3N5O6S3/c1-46(2)20-18-42(34-8-12-37(48)13-9-34)36(31-46)32-55-22-24-56(25-23-55)39-14-10-35(11-15-39)45(57)53-65(60,61)41-16-17-43(44(30-41)64(58,59)47(49,50)51)52-38(19-21-54-26-28-62-29-27-54)33-63-40-6-4-3-5-7-40/h3-17,30,38,52H,18-29,31-33H2,1-2H3,(H,53,57)/t38-/m1/s1/i26D2,27D2,28D2,29D2 |
| IUPAC | 4-[4-[[2-(4-chlorophenyl)-5,5-dimethylcyclohexen-1-yl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-(2,2,3,3,5,5,6,6-octadeuteriomorpholin-4-yl)-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
ABT 263-d8 is a deuterated analog of ABT-263, which is a potent inhibitor of anti-apoptotic proteins Bcl-2, Bcl-xL, and Bcl-w. These anti-apoptotic proteins are responsible for inhibiting programmed cell death, which makes them an attractive target for cancer therapy. ABT 263-d8 is used for research purposes to understand the mechanism of action of ABT-263 in cancer cells and to develop more effective cancer treatments.
The chemical formula of ABT 263-d8 is C47H37D8Cl2N5O5S2, which contains eight deuterium atoms in the molecular structure. The molecular weight of ABT 263-d8 is 901.04 g/mol. ABT 263-d8 is a white solid powder that is soluble in DMSO, ethanol, and methanol.
ABT 263-d8 is typically used in cell-based assays and in vivo studies to evaluate the efficacy of ABT-263 in cancer therapy. The deuterated analog is used to track the pharmacokinetics and pharmacodynamics of ABT-263 in vivo, which provides valuable information for drug development. The deuterium atoms in ABT 263-d8 also increase the stability of the compound, which improves its shelf-life and makes it more suitable for research purposes.
In conclusion, ABT 263-d8 is a valuable tool for cancer research that provides insights into the mechanism of action of ABT-263 and helps to develop more effective cancer treatments.
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