3-O-Acetyl Ezetimibe-d4
| Product Name | 3-O-Acetyl Ezetimibe-d4 |
|---|---|
| Alternate Names | Ezetimibe Stable Isotopes, Stable Isotopes of Ezetimibe |
| CAT No. | CS-T-64364 |
| CAS No. | 1217642-08-4 |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Ezetimibe |
| Smileys | O=C1N(C2=C([2H])C([2H])=C(F)C([2H])=C2[2H])[C@H](C3=CC=C(O)C=C3)[C@H]1CC[C@H](OC(C)=O)C4=CC=C(F)C=C4 |
| Canonical Smiles | CC(=O)OC(CCC1C(N(C1=O)C2=CC=C(C=C2)F)C3=CC=C(C=C3)O)C4=CC=C(C=C4)F |
| InchIKey | HFQRXXWTCQBULQ-RXBMDDDJSA-N |
| Inchl | InChI=1S/C26H23F2NO4/c1-16(30)33-24(17-2-6-19(27)7-3-17)15-14-23-25(18-4-12-22(31)13-5-18)29(26(23)32)21-10-8-20(28)9-11-21/h2-13,23-25,31H,14-15H2,1H3/t23-,24+,25-/m1/s1/i8D,9D,10D,11D |
| IUPAC | [(1S)-1-(4-fluorophenyl)-3-[(2S,3R)-2-(4-hydroxyphenyl)-4-oxo-1-(2,3,5,6-tetradeuterio-4-fluorophenyl)azetidin-3-yl]propyl] acetate |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
3-O-Acetyl Ezetimibe-d4, also known as Ezetimibe-d4 Acetate, is a deuterated analog of 3-O-Acetyl Ezetimibe, which is a medication used for the treatment of high cholesterol levels in the blood. 3-O-Acetyl Ezetimibe-d4 is chemically synthesized by the acetylation of Ezetimibe-d4, which is a deuterated form of Ezetimibe.
The chemical structure of 3-O-Acetyl Ezetimibe-d4 consists of a phenylpiperazine moiety and a substituted azetidine ring. It functions as a cholesterol absorption inhibitor by blocking the Niemann-Pick C1-like 1 (NPC1L1) receptor in the intestine, which is responsible for the uptake of cholesterol from the diet. This inhibition reduces the amount of cholesterol that enters the bloodstream, leading to lower levels of LDL cholesterol (the "bad" cholesterol).
3-O-Acetyl Ezetimibe-d4 is commonly used in biochemical research to study the mechanism of action of Ezetimibe and its derivatives. The deuterated form of the compound is useful in mass spectrometry, as it allows for accurate analysis of the metabolism and pharmacokinetics of the drug in vivo.
In conclusion, 3-O-Acetyl Ezetimibe-d4 is a deuterated analog of Ezetimibe, which is used for the treatment of high cholesterol levels. It functions by inhibiting cholesterol absorption in the intestine, and is commonly used in biochemical research to study its mechanism of action.
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Related Compounds
Ezetimibe D4 | Ezetimibe Hydroxy-d4 β-D-Glucuronide | Rac Ezetimibe D4 | Ezetimibe D4 (4-Fluorophenyl-2,3,5,6-d4) | Ezetimibe N-Phenyl-D4 Phenoxy Glucuronide | Ezetimibe 13C6 | Ezetimibe-d4 Diacetate | Ezetimibe-D4 Phenoxy Glucuronide |