Acetylcholine-1,1,2,2-d4 Bromide

Acetylcholine-1,1,2,2-d4 Bromide is a stable isotope-labelled derivative of the neurotransmitter acetylcholine. It is used in neuroscience research as a tracer to study the synthesis, release, and metabolism of acetylcholine in the brain. Acetylcholine is an important neurotransmitter that plays a crucial role in learning, memory, and muscle movement. Dysfunction in the cholinergic system has been implicated in numerous neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and schizophrenia. Acetylcholine-1,1,2,2-d4 Bromide is typically administered through injection and is rapidly metabolized in the body. Upon injection, it is taken up by cholinergic neurons and incorporated into newly synthesized acetylcholine molecules. Researchers can then track the distribution and fate of the labelled acetylcholine using techniques such as autoradiography or liquid chromatography-mass spectrometry. The chemical formula for Acetylcholine-1,1,2,2-d4 Bromide is C7H16D4BrNO2, and it has a molecular weight of 244.09 g/mol. The compound is a white crystalline powder that is soluble in water and ethanol. It is stable under normal laboratory conditions and can be stored at room temperature for extended periods. In conclusion, Acetylcholine-1,1,2,2-d4 Bromide is a valuable tool for studying the cholinergic system in the brain. Its stable isotope label allows researchers to track the fate of acetylcholine in vivo, providing insights into the mechanisms underlying neurological and psychiatric disorders.