4-Acetoxynisoldipine-d6
| Product Name | 4-Acetoxynisoldipine-d6 |
|---|---|
| Alternate Names | Nisoldipine Stable Isotopes, Stable Isotopes of Nisoldipine |
| CAT No. | CS-T-64439 |
| CAS No. | 1189672-21-6 |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Nisoldipine |
| Smileys | O=C(C1=C(C)N([2H])C(C[2H])=C(C(OC)=O)C1C2=C([2H])C([2H])=C([2H])C([2H])=C2[N+]([O-])=O)OCC(C)(OC(C)=O)C |
| Canonical Smiles | CC1=C(C(C(=C(N1)C)C(=O)OCC(C)(C)OC(=O)C)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC |
| InchIKey | IVTRFZZAHBRCGQ-RKAHMFOGSA-N |
| Inchl | InChI=1S/C22H26N2O8/c1-12-17(20(26)30-6)19(15-9-7-8-10-16(15)24(28)29)18(13(2)23-12)21(27)31-11-22(4,5)32-14(3)25/h7-10,19,23H,11H2,1-6H3/i4D3,5D3 |
| IUPAC | 5-O-[2-acetyloxy-3,3,3-trideuterio-2-(trideuteriomethyl)propyl] 3-O-methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
4-Acetoxynisoldipine-d6 is a labeled isotopic form of 4-Acetoxynisoldipine, a calcium channel blocker. It is used in pharmacological studies to determine the pharmacokinetic properties and metabolic pathways of the drug. The deuterium labeled compound allows for differentiation between the labeled and unlabeled forms of the drug in biological samples, aiding in the analysis of drug metabolism.
Chemically, 4-Acetoxynisoldipine-d6 is a derivative of nisoldipine, a dihydropyridine calcium channel blocker. It contains a deuterium atom at the 6-position of the acetoxyl group. The compound works by blocking the influx of calcium ions into smooth muscle cells, leading to relaxation of the blood vessels and a reduction in blood pressure. The labeled compound is structurally similar to the unlabeled form, with the only difference being the presence of the deuterium atom.
The usage of 4-Acetoxynisoldipine-d6 in pharmacological studies provides valuable information on the metabolic fate of the drug in vivo. It allows for the identification of metabolites and their formation pathways, aiding in the development of more effective and safer drugs. The compound's labeled form also aids in the determination of drug-drug interactions and drug distribution within the body. Overall, 4-Acetoxynisoldipine-d6 is a useful tool in pharmacological research, providing insights into the metabolism and pharmacokinetics of nisoldipine.
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Related Compounds
Nisoldipine D4 | Dehydro Nisoldipine-d7 | Nisoldipine D6 |