N6-Acryloyl Ibrutinib

Product Name N6-Acryloyl Ibrutinib
Alternate Names Ibrutinib Impurities, Impurities of Ibrutinib
CAT No. CS-T-64851
CAS No. 2031255-27-1
Category Impurities
Stock IN-Stock
Mol. Wt. 494.54 g/mol
Mol. For. C₂₈H₂₆N₆O₃
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Ibrutinib
Smileys C=CC(N1C[C@H](N2N=C(C3=CC=C(OC4=CC=CC=C4)C=C3)C5=C(NC(C=C)=O)N=CN=C52)CCC1)=O
Controlled No
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N6-Acryloyl Ibrutinib is a chemical compound used in the development of inhibitors for Bruton's tyrosine kinase (BTK). BTK is an enzyme that plays a crucial role in the activation of B cells, which are responsible for the production of antibodies. Inhibiting BTK has been shown to be an effective treatment for certain types of cancers, such as B-cell lymphomas and leukemias. N6-Acryloyl Ibrutinib is synthesized by reacting Ibrutinib, a known BTK inhibitor, with acrylic acid. The resulting compound is a derivative of Ibrutinib with an acryloyl group attached to the N6 position. This modification enhances the potency of the inhibitor and improves its selectivity for BTK over other kinases. In addition to its use in cancer treatment, N6-Acryloyl Ibrutinib has also been studied for its potential as an anti-inflammatory agent. BTK has been implicated in the regulation of inflammatory responses, and inhibiting its activity may have therapeutic benefits for diseases such as rheumatoid arthritis and asthma. Overall, N6-Acryloyl Ibrutinib is a promising compound in the development of targeted cancer therapies and may have potential applications in the treatment of inflammatory diseases.

Related Compounds

ibrutinib acetyl impurity | Ibrutinib Impurity 15 | Rac -Ibrutinib propionaldehyde | Ibrutinib Impurity 7 | Ibrutinib N-Oxide impurity | N-Desacryloyl N-(3-Acryloyl-propanoyl) Ibrutinib | Ibrutinib Michael addition adduct | Ibrutinib Dimer | Ibrutinib Impurity 12 | Ibrutinib Impurity 6 | Ibrutinib Di-piperidine impurity | Ibrutinib impurity Dimer | Ibrutinib Impurity 9 | Ibrutinib Piperidine impurity | Ibrutinib Impurity 1 | N1-(2-Carboxyethyl) Ibrutinib | Ibrutinib Piperidine N-desacryl impurity | Ibrutinib Impurity D | Ibrutinib Impurity 8 | N-Desacryloyl N-3-hydroxypropanoyl Ibrutinib | Ibrutinib Amino Piperidine dihydrochloride Impurity | Ibrutinib Impurity 42 | Ibrutinib (IBR) Diamine Impurity | Ibrutinib Impurity L | Ibrutinib impurity 25 | Ibrutinib Hydroxy Impurity | Ibrutinib N1-Oxide |

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