(R)-N-(2-acetyl-1,2,3,4-tetrahydro-5,8-dimethoxy-2-naphthalenyl)-acetamide-13C

(R)-N-(2-acetyl-1,2,3,4-tetrahydro-5,8-dimethoxy-2-naphthalenyl)-acetamide-13C, also known as Nefopam-13C, is a chemical compound used primarily as an analgesic medication. This compound is a labeled version of the drug Nefopam, which is used to relieve pain, particularly in cases of postoperative pain, chronic pain, and neuropathic pain. Nefopam-13C works by inhibiting the reuptake of the neurotransmitters serotonin, norepinephrine, and dopamine in the central nervous system. This leads to an increase in the levels of these neurotransmitters, which in turn reduces pain perception. Nefopam-13C is a chiral compound, meaning it has two enantiomers that are mirror images of each other. The (R)-enantiomer is believed to be the active form of the drug, while the (S)-enantiomer is inactive. The chemical structure of Nefopam-13C consists of a naphthalene ring with two methoxy groups and an acetyl group attached to it. The compound also contains an amide group and a labeled carbon-13 atom. The molecular formula of Nefopam-13C is C17H20DNO4, and the molecular weight is 301.4 g/mol. Nefopam-13C is typically administered orally in the form of tablets or capsules. The recommended dosage varies depending on the patient's age, weight, and medical condition. Like all medications, Nefopam-13C may cause side effects such as nausea, vomiting, dizziness, and headache. It is important to consult a healthcare professional before taking this medication.