2-Amino-6,8-dihydroxypurine-15N5

2-Amino-6,8-dihydroxypurine-15N5, also known as Adenine-15N5, is a stable isotope-labeled version of adenine, a purine nucleobase found in DNA and RNA. This compound is a key building block of nucleotides, which are the basic units of nucleic acids. Adenine-15N5 is used in a variety of biochemical and analytical applications, including mass spectrometry, metabolic labeling, and tracing experiments. Adenine-15N5 is commonly used in mass spectrometry-based proteomics studies to quantify protein expression levels and determine protein-protein interactions. The stable isotope labeling allows for accurate and sensitive detection of small changes in protein abundance and dynamics. Additionally, Adenine-15N5 has been used in metabolic labeling studies to investigate cellular pathways and metabolic fluxes. In terms of chemical information, Adenine-15N5 has a molecular formula of C5H4N5O and a molecular weight of 152.12 g/mol. It is a white to off-white powder that is soluble in water and has a melting point of 360-365°C. Adenine-15N5 is stable under normal conditions and does not pose any significant health hazards. However, it should be handled with care and stored in a cool, dry place away from sources of heat and light.