(S)-N-(1-Amino-1-oxobutan-2-yl)-4-chlorobutanamide-d3

(S)-N-(1-Amino-1-oxobutan-2-yl)-4-chlorobutanamide-d3, also known as Leucine-d3, is a deuterated form of the amino acid leucine. It is commonly used in metabolic research as a tracer for studying protein turnover and muscle metabolism. Leucine-d3 is a stable isotope of leucine, which means that it behaves identically to the non-deuterated form in chemical reactions, but can be easily distinguished and measured using mass spectrometry. Leucine-d3 is typically administered orally or intravenously, and is incorporated into newly synthesized proteins in the body. By measuring the levels of leucine-d3 in the blood or urine, researchers can track the rate of protein synthesis and breakdown, as well as the overall turnover of proteins in different tissues. This information can be used to better understand the mechanisms underlying muscle growth and repair, as well as the effects of different nutritional or exercise interventions on protein metabolism. In addition to its use in metabolic research, leucine-d3 is also used in the production of stable isotope-labeled peptides and proteins for use in mass spectrometry-based proteomics. It is a valuable tool for identifying and quantifying specific proteins in complex biological samples, and has applications in fields such as drug discovery and biomarker identification. Overall, leucine-d3 is a versatile and important tool for studying protein metabolism and identifying new targets for therapeutic intervention.