Antrafenine-d8 Dihydrochloride

Product Name Antrafenine-d8 Dihydrochloride
CAT No. CS-T-66286
CAS No. 1329809-16-6
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Smileys O=C(OCCN1C([2H])([2H])C([2H])([2H])N(C2=CC=CC(C(F)(F)F)=C2)C([2H])([2H])C1([2H])[2H])C3=CC=CC=C3NC4=CC=NC5=CC(C(F)(F)F)=CC=C45.[H]Cl.[H]Cl
Canonical Smiles C1CN(CCN1CCOC(=O)C2=CC=CC=C2NC3=C4C=CC(=CC4=NC=C3)C(F)(F)F)C5=CC=CC(=C5)C(F)(F)F
InchIKey NWGGKKGAFZIVBJ-DHNBGMNGSA-N
Inchl InChI=1S/C30H26F6N4O2/c31-29(32,33)20-4-3-5-22(18-20)40-14-12-39(13-15-40)16-17-42-28(41)24-6-1-2-7-25(24)38-26-10-11-37-27-19-21(30(34,35)36)8-9-23(26)27/h1-11,18-19H,12-17H2,(H,37,38)/i12D2,13D2,14D2,15D2
IUPAC 2-[2,2,3,3,5,5,6,6-octadeuterio-4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl 2-[[7-(trifluoromethyl)quinolin-4-yl]amino]benzoate
Controlled No
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Antrafenine-d8 Dihydrochloride is a deuterated form of Antrafenine Dihydrochloride, which is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of pain and inflammation. The deuterium labeling of Antrafenine-d8 Dihydrochloride provides a unique tool for researchers studying the pharmacokinetics and metabolism of Antrafenine in vivo. The chemical formula for Antrafenine-d8 Dihydrochloride is C14H9D8Cl2NO2 and its chemical structure is similar to that of Antrafenine Dihydrochloride, except that eight hydrogen atoms in the molecule have been replaced with deuterium atoms. This labeling does not affect the therapeutic activity of the drug but allows for better understanding of its metabolic pathways and elimination from the body. Antrafenine-d8 Dihydrochloride is typically administered orally as a tablet or capsule and is rapidly absorbed into the bloodstream. The drug works by inhibiting the activity of cyclooxygenase (COX), an enzyme responsible for the production of prostaglandins, which are mediators of pain and inflammation. Antrafenine-d8 Dihydrochloride is metabolized in the liver and excreted primarily in the urine. In conclusion, Antrafenine-d8 Dihydrochloride is a useful tool for researchers studying the pharmacokinetics and metabolism of Antrafenine. Its deuterium labeling provides a unique method for tracking the drug's movement within the body and can aid in the development of safer and more effective NSAIDs in the future.

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