5-[[3-Bromo-4-(2-cyclohexylethoxy)phenyl]methylene]-2,4-thiazolidinedione-d4

5-[[3-Bromo-4-(2-cyclohexylethoxy)phenyl]methylene]-2,4-thiazolidinedione-d4 is a deuterated derivative of 5-[[3-Bromo-4-(2-cyclohexylethoxy)phenyl]methylene]-2,4-thiazolidinedione, which is a potent and selective peroxisome proliferator-activated receptor gamma (PPARγ) agonist. PPARγ is a nuclear receptor that plays a crucial role in regulating glucose and lipid metabolism, and its activation has been shown to improve insulin sensitivity, reduce inflammation, and promote adipocyte differentiation. 5-[[3-Bromo-4-(2-cyclohexylethoxy)phenyl]methylene]-2,4-thiazolidinedione-d4 is commonly used in metabolic research to study the effects of PPARγ activation on various physiological processes. Its deuterated form is useful in pharmacokinetic studies, where it can be used to track the metabolism and distribution of the compound in vivo. The chemical formula of 5-[[3-Bromo-4-(2-cyclohexylethoxy)phenyl]methylene]-2,4-thiazolidinedione-d4 is C19H16BrD4N2O3S, and its molecular weight is 460.38 g/mol. It is a yellowish powder that is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and ethanol. Overall, 5-[[3-Bromo-4-(2-cyclohexylethoxy)phenyl]methylene]-2,4-thiazolidinedione-d4 is an important tool for researchers studying PPARγ and its effects on metabolic pathways, and its deuterated form is useful for pharmacokinetic studies.