4-Carboxy Tolbutamide-d9 Ethyl Ester

4-Carboxy Tolbutamide-d9 Ethyl Ester is a deuterated analog of the drug Tolbutamide, which is used to treat diabetes mellitus type 2. The deuterated version is used in research studies to investigate the pharmacokinetics and metabolism of Tolbutamide in vivo. The chemical formula of 4-Carboxy Tolbutamide-d9 Ethyl Ester is C14H11D9N2O4S, and it has a molecular weight of 349.44 g/mol. It is a white to off-white powder that is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and ethanol. The drug works by stimulating the release of insulin from the pancreas, which helps to lower blood glucose levels. It is metabolized in the liver and excreted in the urine. The deuterated version allows researchers to track the drug's metabolism and excretion using mass spectrometry. The drug is typically administered orally in tablet form, and the dosage is individualized based on the patient's response to treatment. It can cause side effects such as hypoglycemia, gastrointestinal disturbances, and skin rash. Patients taking the drug should be closely monitored for any adverse effects. In conclusion, 4-Carboxy Tolbutamide-d9 Ethyl Ester is a useful tool for investigating the pharmacokinetics and metabolism of Tolbutamide in vivo. Its chemical formula and molecular weight make it easy to handle and study, while its solubility in organic solvents allows for versatile usage. It is an important tool in diabetes research and has the potential to improve our understanding of the mechanisms underlying diabetes mellitus type 2.