4-Carboxy Tolbutamide-d9
| Product Name | 4-Carboxy Tolbutamide-d9 |
|---|---|
| CAT No. | CS-T-69995 |
| CAS No. | 1184973-50-9 |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Smileys | CCCCNC(=O)NS(=O)(=O)C1=CC=C(C=C1)C(=O)O |
| Canonical Smiles | CCCCNC(=O)NS(=O)(=O)C1=CC=C(C=C1)C(=O)O |
| InchIKey | GCMVATDSSHTCOS-KMQVRKNJSA-N |
| Inchl | InChI=1S/C12H16N2O5S/c1-2-3-8-13-12(17)14-20(18,19)10-6-4-9(5-7-10)11(15)16/h4-7H,2-3,8H2,1H3,(H,15,16)(H2,13,14,17)/i2D2,3D2,8D2 |
| IUPAC | 4-(1,1,2,2,3,3-hexadeuteriobutylcarbamoylsulfamoyl)benzoic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
4-Carboxy Tolbutamide-d9 is a deuterated analogue of the antidiabetic drug Tolbutamide. It is a labeled compound that is used in pharmacokinetic studies to determine the metabolic fate of Tolbutamide in vivo.
Tolbutamide is a first-generation sulfonylurea drug that is used to treat type 2 diabetes. It works by stimulating the release of insulin from the pancreatic beta cells, which helps to lower blood glucose levels. Tolbutamide is metabolized in the liver by cytochrome P450 enzymes to form several metabolites, including 4-Carboxy Tolbutamide.
4-Carboxy Tolbutamide-d9 is chemically identical to 4-Carboxy Tolbutamide, except that it contains deuterium atoms at specific positions. Deuterium is a heavy isotope of hydrogen that is often used in metabolic studies because it does not significantly alter the chemical properties of the molecule.
The use of 4-Carboxy Tolbutamide-d9 allows researchers to track the metabolic fate of Tolbutamide in vivo. By administering a dose of Tolbutamide-d9 to a subject and measuring the levels of 4-Carboxy Tolbutamide-d9 in the blood and urine over time, researchers can determine the rate of metabolism of Tolbutamide. This information can be used to optimize dosing regimens and improve the safety and efficacy of Tolbutamide therapy.
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