N-Desaminomethylsulfonyl-N-nitryl Dofetilide
| Product Name | N-Desaminomethylsulfonyl-N-nitryl Dofetilide |
|---|---|
| Alternate Names | Dofetilide Impurities, Impurities of Dofetilide |
| CAT No. | CS-T-73448 |
| CAS No. | 115256-45-6 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 393.46 g/mol |
| Mol. For. | C₁₈H₂₃N₃O₅S |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Dofetilide |
| Smileys | CS(=O)(NC1=CC=C(CCN(C)CCOC2=CC=C([N+]([O-])=O)C=C2)C=C1)=O |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
N-Desaminomethylsulfonyl-N-nitryl Dofetilide (also known as NDM-N-NO2-Dofetilide) is a chemical compound that belongs to the class of drugs known as antiarrhythmics. It is a derivative of Dofetilide, which is commonly used to treat irregular heartbeat or arrhythmia. NDM-N-NO2-Dofetilide is a potent and selective inhibitor of the rapid component of the delayed rectifier potassium current (IKr) which is responsible for repolarization of the heart.
NDM-N-NO2-Dofetilide has been shown to be effective in treating a variety of arrhythmias, including atrial fibrillation, atrial flutter, and ventricular tachycardia. It works by blocking the potassium channels in the heart, which slows the rate of electrical impulses and helps to restore a normal heart rhythm.
NDM-N-NO2-Dofetilide is mainly administered intravenously in hospitals and clinics under close medical supervision. It is important to note that this drug has a narrow therapeutic window, which means that the dosage must be carefully monitored to avoid potential side effects such as QT interval prolongation, a potentially life-threatening condition.
In conclusion, N-Desaminomethylsulfonyl-N-nitryl Dofetilide is a potent antiarrhythmic drug that has shown great promise in treating various types of arrhythmias. Its usage requires careful monitoring and administration under medical supervision due to its narrow therapeutic window and potential side effects.
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Related Compounds
N,N'-Dimethylsulfonyl Dofetilide | N-Methylsulfonyl Dofetilide | N’-Desaminomethylsulfonyl-N’-nitryl Dofetilide | N’-Methylsulfonyl Dofetilide(MIXTURE) | N-desmethyl N-Nitroso Dofetilide | N-Desmethylsulfonyl-N’-methylsulfonyl Dofetilide | Dofetilide impurity E | N-Desmethyl Dofetilide | N-Desmethylsulfonyl Dofetilide Dihydrochloride | N’-Desmethylsulfonyl-N-methylsulfonyl Dofetilide | N’-Desmethylsulfonyl Dofetilide | N-Nitroso Dofetilide impurity 2 |