Deschloro Amlodipine

Chemical Name Deschloro Amlodipine
Alternate Names Amlodipine Impurities, Impurities of Amlodipine
CAT No. CS-T-73778
CAS Registry# 88150-52-1
Category Impurities
Stock IN-Stock
Mol. Wt. 374.4 g/mol
Mol. For. C20H26N2O5
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Amlodipine
Purity 95%
Smileys O=C(C1=C(COCCN)NC(C)=C(C(OC)=O)C1C2=CC=CC=C2)OCC
Controlled No
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Deschloro Amlodipine (DCA) is a chemical compound that is commonly used as a calcium channel blocker (CCB) in the treatment of hypertension and angina. It is a derivative of amlodipine, a popular dihydropyridine CCB that works by blocking the influx of calcium ions into cardiac and smooth muscle cells, leading to vasodilation and reduced blood pressure. DCA differs from amlodipine in that it lacks a chlorine atom in its chemical structure. DCA has been shown to have similar pharmacological properties to amlodipine, with studies demonstrating its effectiveness in reducing blood pressure and improving symptoms of angina. Additionally, it has been suggested that DCA may have a longer half-life than amlodipine, potentially leading to better and more sustained therapeutic effects. In terms of chemical information, DCA has a molecular weight of 408.95 g/mol and a chemical formula of C20H24N2O5. It is a white to off-white powder that is insoluble in water but soluble in organic solvents such as ethanol and dimethyl sulfoxide. DCA is typically administered orally in tablet form, with dosages ranging from 2.5 mg to 10 mg per day depending on the patient's condition and response to treatment. Overall, DCA represents a promising alternative to amlodipine in the treatment of hypertension and angina, with its unique chemical structure and potential for improved pharmacokinetic properties making it a valuable addition to the CCB class of medications.

Related Compounds

Amlodipine N-Galactose | Amlodipine EP Impurity H | Amlodipine Impurity 61 | Amlodipine Impurity 8 | Amlodipine EP Impurity B | Dehydro Amlodipine N-Oxide | Amlodipine EP Impurity G | Di-acid Amlodipine | Amlodipine For Peak Identification | Amlodipine Impurity 19 | Amlodipine Azido Impurity | Amlodipine Impurity F Maleate | Amlodipine Galactose Adduct | Amlodipine Mannitol Adduct Acetate Salt | Amlodipine Impurity | R-Amlodipine Besilate | Amlodipine Impurity 38 | Amlodipine Mannitol Adduct | Amlodipine EP Impurity D Oxalate Salt | Amlodipine morpholine impurity | Amlodipine Lactose adduct | Dimethoxy Impurity Deschloro Amlodipine | Amlodipine Impurity 29 | Amlodipine EP Impurity C | Amlodipine Impurity 25 | Atorvastatin Amlodipine Dimer | Phthaloyl Amlodipine Dimethyl Ester | Atorvastatin-Amlodipine Adduct | N-Nitroso Amlodipine EP Impurity F | Amlodipine Besylate Impurity D Besylate salt | Amlodipine Impurity 9 | Amlodipine Methyl Ester | Amlodipine Nitroso Impurity | Amlodipine orotate | Amlodipine Impurity 34 | N-Nitroso Amlodipine | Amlodipine EP Impurity E | Amlodipine Aspartic Acid Impurity | N-Fomyl Amlodipine | Hydroxyethyl phthalyl amlodipine | Amlodipin EP Impurity D | Amlodipine Impurity 32 | Amlodipine EP Impurity D HCl | Amlodipine EP Impurity E Maleate | Amlodipine EP Impurity A | Amlodipine N-Lactoside | Desmethyl Amlodipine | Amlodipine Mannitol Adduct HCl Salt | Amlodipine EP Impurity F | R-Amlodipine hemipentahydrate | Amlodipine Related Compound A | Amlodipine aminoethyl |

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