7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin-d3

Product Name 7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin-d3
Alternate Names Camptothecin Stable Isotopes, Stable Isotopes of Camptothecin
CAT No. CS-T-76120
CAS No. 1217625-98-3
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Camptothecin
Smileys O=C1C(COC(C2(O)CC)=O)=C2C=C3N1CC4=C3N=C5C=CC(OC(N6CCC(N)CC6)=O)=CC5=C4CC([2H])([2H])[2H]
Canonical Smiles CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N
InchIKey APWFTHDYKJHNEV-TVECXBKPSA-N
Inchl InChI=1S/C28H30N4O6/c1-3-17-18-11-16(38-27(35)31-9-7-15(29)8-10-31)5-6-22(18)30-24-19(17)13-32-23(24)12-21-20(25(32)33)14-37-26(34)28(21,36)4-2/h5-6,11-12,15,36H,3-4,7-10,13-14,29H2,1-2H3/t28-/m0/s1/i1D3
IUPAC [(19S)-19-ethyl-19-hydroxy-14,18-dioxo-10-(2,2,2-trideuterioethyl)-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl] 4-aminopiperidine-1-carboxylate
Controlled No
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7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin-d3 is a potent anticancer drug that is used in the treatment of various types of cancer. It is a derivative of camptothecin and is known for its ability to inhibit the activity of topoisomerase I, an enzyme that plays a crucial role in DNA replication and repair. This inhibition prevents cancer cells from dividing and growing, ultimately leading to their death. As a chemical compound, 7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin-d3 is a complex molecule that contains several functional groups, including a carbonyl group, an amine group, and a piperidine ring. Its chemical formula is C26H26D3N3O6, and it has a molecular weight of 493.57 g/mol. In terms of usage, 7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin-d3 is typically administered intravenously in a hospital or clinical setting. It is used to treat a range of cancers, including ovarian cancer, lung cancer, and colorectal cancer, among others. The drug is often given in combination with other chemotherapy drugs to maximize its effectiveness. While 7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin-d3 is a powerful anticancer drug, it can also have significant side effects. These can include nausea, vomiting, diarrhea, hair loss, and an increased risk of infection. Patients receiving this drug will typically be closely monitored by their healthcare team to ensure that any side effects are managed appropriately.

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