7-Ethyl-10-(4-N-aminopentanoic acid)-1-piperidino)carbonyloxycamptothecin-d3

Product Name 7-Ethyl-10-(4-N-aminopentanoic acid)-1-piperidino)carbonyloxycamptothecin-d3
Alternate Names Camptothecin Stable Isotopes, Stable Isotopes of Camptothecin
CAT No. CS-T-76562
CAS No. 1217816-76-6
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Camptothecin
Smileys O=C1C(COC(C2(O)CC)=O)=C2C=C3N1CC4=C3N=C5C=CC(OC(N6CCC(NCCCCC(O)=O)CC6)=O)=CC5=C4CC([2H])([2H])[2H]
Canonical Smiles CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)NCCCCC(=O)O
InchIKey BSVVZICJFYZDJJ-MLZAFXDMSA-N
Inchl InChI=1S/C33H38N4O8/c1-3-21-22-15-20(45-32(42)36-13-10-19(11-14-36)34-12-6-5-7-28(38)39)8-9-26(22)35-29-23(21)17-37-27(29)16-25-24(30(37)40)18-44-31(41)33(25,43)4-2/h8-9,15-16,19,34,43H,3-7,10-14,17-18H2,1-2H3,(H,38,39)/t33-/m0/s1/i1D3
IUPAC 5-[[1-[[(19S)-19-ethyl-19-hydroxy-14,18-dioxo-10-(2,2,2-trideuterioethyl)-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl]oxycarbonyl]piperidin-4-yl]amino]pentanoic acid
Controlled No
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7-Ethyl-10-(4-N-aminopentanoic acid)-1-piperidino)carbonyloxycamptothecin-d3 is a chemical compound that is used in the medical field as an anti-cancer drug. It is a derivative of camptothecin, which is a natural alkaloid found in the bark and stem of the Chinese tree Camptotheca acuminata. This derivative has been modified to increase its potency and effectiveness against cancer cells. This compound works by inhibiting the activity of an enzyme called topoisomerase I, which is responsible for unwinding DNA during cell division. By inhibiting this enzyme, the compound prevents cancer cells from replicating and eventually leads to their death. It is particularly effective against certain types of cancer, such as ovarian, small cell lung, and colon cancer. 7-Ethyl-10-(4-N-aminopentanoic acid)-1-piperidino)carbonyloxycamptothecin-d3 is typically administered through intravenous infusion and requires close monitoring by a healthcare professional. Common side effects include nausea, vomiting, diarrhea, and hair loss. However, these side effects are usually temporary and can be managed with medication. Overall, this compound represents an important advancement in the treatment of cancer and is a promising option for patients who are seeking effective and targeted therapies.

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