7-Ethyl-d3-camptothecin
| Product Name | 7-Ethyl-d3-camptothecin |
|---|---|
| Alternate Names | Camptothecin Stable Isotopes, Stable Isotopes of Camptothecin |
| CAT No. | CS-T-77290 |
| CAS No. | 1217626-02-2 |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 395.42 g/mol |
| Mol. For. | C₂₂H₁₇D₃N₂O₅ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Camptothecin |
| Smileys | O=C1C(COC(C2(O)CC)=O)=C2C=C(C3=NC4=CC=CC=C45)N1CC3=C5CC([2H])([2H])[2H] |
| Canonical Smiles | CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=CC=CC=C51 |
| InchIKey | MYQKIWCVEPUPIL-MVTYLIICSA-N |
| Inchl | InChI=1S/C22H20N2O4/c1-3-12-13-7-5-6-8-17(13)23-19-14(12)10-24-18(19)9-16-15(20(24)25)11-28-21(26)22(16,27)4-2/h5-9,27H,3-4,10-11H2,1-2H3/t22-/m0/s1/i1D3 |
| IUPAC | (19S)-19-ethyl-19-hydroxy-10-(2,2,2-trideuterioethyl)-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
7-Ethyl-d3-camptothecin is a synthetic derivative of the natural alkaloid camptothecin. It is a potent topoisomerase inhibitor and has been studied for use in cancer treatment. Topoisomerases are enzymes that regulate the supercoiling of DNA during replication and transcription. Inhibition of these enzymes by 7-Ethyl-d3-camptothecin results in DNA damage and apoptosis of cancer cells.
Chemically, 7-Ethyl-d3-camptothecin has a molecular formula of C22H19D3N2O5 and a molecular weight of 415.47 g/mol. It is a yellow crystalline powder that is sparingly soluble in water but soluble in organic solvents such as dimethyl sulfoxide (DMSO) and ethanol.
The usage of 7-Ethyl-d3-camptothecin in cancer treatment is still in the preclinical stage. Studies have shown promising results in inhibiting the growth of various cancer cell lines such as lung, ovarian, and breast cancer. Additionally, it has been found to be effective in overcoming drug resistance in cancer cells.
However, more research is needed to determine the optimal dosage and administration of 7-Ethyl-d3-camptothecin in cancer treatment. Clinical trials are ongoing to evaluate its safety and efficacy. Overall, 7-Ethyl-d3-camptothecin has the potential to be an effective cancer treatment drug and is an important area of study in oncology research.
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