(R)-(-)-Etodolac-d3
| Product Name | (R)-(-)-Etodolac-d3 |
|---|---|
| Alternate Names | Etodolac Stable Isotopes, Stable Isotopes of Etodolac |
| CAT No. | CS-T-77302 |
| CAS No. | 1246815-33-7 |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Etodolac |
| Smileys | CCC1(CC(O)=O)OCCC2=C1NC3=C2C=CC=C3CC([2H])([2H])[2H] |
| Canonical Smiles | CCC1=C2C(=CC=C1)C3=C(N2)C(OCC3)(CC)CC(=O)O |
| InchIKey | NNYBQONXHNTVIJ-NVNSKBCASA-N |
| Inchl | InChI=1S/C17H21NO3/c1-3-11-6-5-7-12-13-8-9-21-17(4-2,10-14(19)20)16(13)18-15(11)12/h5-7,18H,3-4,8-10H2,1-2H3,(H,19,20)/t17-/m1/s1/i2D3 |
| IUPAC | 2-[(1R)-8-ethyl-1-(2,2,2-trideuterioethyl)-4,9-dihydro-3H-pyrano[3,4-b]indol-1-yl]acetic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
(R)-(-)-Etodolac-d3 is a deuterated form of the non-steroidal anti-inflammatory drug (NSAID) Etodolac. NSAIDs are commonly used to relieve pain, reduce inflammation, and lower fevers. The deuterated form of Etodolac has three deuterium atoms replacing three of the hydrogen atoms in the molecule. This modification helps in studying the pharmacokinetic and metabolic properties of the drug.
Etodolac is a selective inhibitor of the cyclooxygenase-2 (COX-2) enzyme which is responsible for the production of prostaglandins that cause inflammation and pain. By inhibiting COX-2, Etodolac-d3 reduces inflammation and pain without affecting the production of other important prostaglandins.
(R)-(-)-Etodolac-d3 is used in pharmacokinetic and metabolic studies to determine the absorption, distribution, metabolism, and excretion of the drug. It is also used in drug-drug interaction studies to understand the effect of other drugs on the pharmacokinetics of Etodolac-d3.
Chemically, (R)-(-)-Etodolac-d3 has a molecular formula of C17H12D3NO3 and a molecular weight of 296.36 g/mol. It is a white to off-white crystalline powder that is stable under normal storage conditions. The drug is administered orally and is rapidly absorbed from the gastrointestinal tract. The elimination half-life of Etodolac-d3 is about 6-7 hours, and the drug is primarily eliminated through the urine.
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Related Compounds
Etodolac D4 | rac Etodolac-d3 |