2-Hydroxy Promazine-d6

2-Hydroxy Promazine-d6 is a deuterated derivative of the antipsychotic drug Promazine. The compound has a molecular formula of C17H13D6N2O2 and a molecular weight of 297.43 g/mol. It is a white to off-white crystalline powder with a purity of at least 98% and can be used as a stable isotopic internal standard for the quantification of Promazine in biological samples. Promazine is a phenothiazine derivative that acts as a dopamine antagonist, used primarily as an antipsychotic for the treatment of schizophrenia and other psychotic disorders. It works by blocking the dopamine receptors in the brain, which are responsible for the transmission of signals involved in the development of psychotic symptoms. The deuterated form of Promazine, 2-Hydroxy Promazine-d6, is used in pharmacokinetic studies to determine the pharmacological properties of Promazine, including its absorption, distribution, metabolism, and excretion. 2-Hydroxy Promazine-d6 is also used to investigate the metabolism of Promazine by studying its metabolites in biological samples. The compound can be added to the sample as an internal standard, allowing for accurate and precise quantification of Promazine and its metabolites. Its deuterated form also allows for differentiation between the natural and synthetic forms of Promazine. Overall, 2-Hydroxy Promazine-d6 is a useful tool for the research and development of antipsychotic drugs and their pharmacokinetics. Its stable isotopic properties and chemical structure make it an ideal internal standard for the quantification and analysis of Promazine and its metabolites in biological samples.