1-[2-Hydroxy-3-(1-naphthalenyloxy)propyl]-2,5-pyrrolidinedione-d7

1-[2-Hydroxy-3-(1-naphthalenyloxy)propyl]-2,5-pyrrolidinedione-d7 is a deuterated analogue of a commonly used pharmaceutical compound that is used to treat a range of medical conditions, including hypertension and congestive heart failure. This compound is labeled with deuterium, a stable isotope of hydrogen, which enhances its stability and extends its half-life in biological systems. The chemical structure of 1-[2-Hydroxy-3-(1-naphthalenyloxy)propyl]-2,5-pyrrolidinedione-d7 consists of a pyrrolidinedione ring with a hydroxyl group and a naphthyl group attached to it via a propyl linker. The deuterium atoms are incorporated into the propyl linker, which does not affect the biological activity of the compound. This compound acts as an angiotensin-converting enzyme (ACE) inhibitor, which inhibits the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. By blocking the action of ACE, this compound helps to relax blood vessels, reduce blood pressure, and improve cardiac function. Overall, 1-[2-Hydroxy-3-(1-naphthalenyloxy)propyl]-2,5-pyrrolidinedione-d7 is an important tool for studying the pharmacokinetics and pharmacodynamics of the parent compound in biological systems. Its stable isotopic labeling allows for accurate quantification of the compound in biological matrices and facilitates the development of more effective and safer pharmaceuticals.