Product Name |
3-Hydroxy Nevirapine-d3 |
Alternate Names |
Nevirapine Stable Isotopes, Stable Isotopes of Nevirapine |
CAT No. |
CS-T-78746
|
CAS No. |
1346602-85-4 |
Category |
Stable Isotopes |
Stock |
Enquire
|
Mol. Wt. |
Not Available |
Mol. For. |
Not Available
|
Hazardous |
This is not a Hazardous Compound
|
COA |
View Sample COA
|
MSDS |
View Sample MSDS
|
Parent API |
Nevirapine |
Smileys |
OC1=CN=C(N(C2CC2)C3=C(C(N4)=O)C=CC=N3)C4=C1C([2H])([2H])[2H] |
Controlled |
No |
Shipping |
Free for purchase above 1000$ |
Delivery |
In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
Return |
Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
Ordering |
Place your order online or by email sales@clearsynth.com |
If you find a better price anywhere else we guarantee Price match.
3-Hydroxy Nevirapine-d3 is a deuterated form of the antiretroviral drug Nevirapine, which is used to treat human immunodeficiency virus (HIV) infection. The deuterium substitution in 3-Hydroxy Nevirapine-d3 enhances the drug's stability and increases its effectiveness in the body.
The main mechanism of action of Nevirapine is to prevent the replication of HIV by inhibiting the reverse transcriptase enzyme, which is essential for viral replication. It is also effective against HIV strains that are resistant to other antiretroviral drugs.
Like its non-deuterated counterpart, 3-Hydroxy Nevirapine-d3 is metabolized in the liver by the cytochrome P450 system, specifically the CYP3A4 enzyme. It is eliminated from the body primarily through the urine, with a half-life of approximately 45 hours.
The usage of 3-Hydroxy Nevirapine-d3 is similar to that of Nevirapine, and it is typically prescribed as part of a combination therapy regimen for HIV treatment. It is available in tablet form, and the dosage is determined by the patient's weight and other individual factors.
In conclusion, 3-Hydroxy Nevirapine-d3 is a deuterated form of Nevirapine that is used in the treatment of HIV infection. Its stability and effectiveness are enhanced by the deuterium substitution, and it is metabolized and eliminated similarly to its non-deuterated counterpart. It is an important addition to the arsenal of antiretroviral drugs used in the fight against HIV.