2-Hydroxy Nevirapine-d3
| Product Name | 2-Hydroxy Nevirapine-d3 |
|---|---|
| Alternate Names | Nevirapine Stable Isotopes, Stable Isotopes of Nevirapine |
| CAT No. | CS-T-79246 |
| CAS No. | 1329834-05-0 |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Nevirapine |
| Smileys | OC1=NC2=C(NC(C3=C(N=CC=C3)N2C4CC4)=O)C(C([2H])([2H])[2H])=C1 |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
2-Hydroxy Nevirapine-d3 is a deuterated analogue of 2-Hydroxy Nevirapine, a non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1 infection. The deuterated form is used in pharmacokinetic studies to evaluate the drug's metabolic pathways, bioavailability, and elimination rate in the body.
2-Hydroxy Nevirapine-d3 is administered orally in tablet form. It is rapidly absorbed from the gastrointestinal tract and undergoes extensive metabolism in the liver by the cytochrome P450 enzyme system. The deuterated form of the drug has been used in studies to evaluate the effect of genetic variations in the CYP2B6 gene on the metabolism of nevirapine.
The chemical structure of 2-Hydroxy Nevirapine-d3 is similar to that of the non-deuterated form, with the exception of three deuterium atoms in the molecule. The deuterium atoms do not affect the pharmacological activity of the drug but are used as a marker for pharmacokinetic studies.
In conclusion, 2-Hydroxy Nevirapine-d3 is a useful tool in studying the pharmacokinetics of nevirapine and evaluating the effect of genetic variations on the metabolism of the drug. Its chemical structure is similar to that of the non-deuterated form, with the exception of three deuterium atoms, which are used as a marker in pharmacokinetic studies.
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Related Compounds
Nevirapine D8 | Nevirapine D4 | Nevirapine D3 | Nevirapine-D4 | Nevirapine D5 |