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2-Hydroxy Hippuric Acid-13C2,15N is a stable isotope-labeled derivative of 2-Hydroxy Hippuric Acid. It is used as an internal standard in mass spectrometry-based metabolomics studies to accurately quantify the levels of 2-Hydroxy Hippuric Acid in biological samples.
2-Hydroxy Hippuric Acid is a metabolite of the amino acid phenylalanine, which is found in high-protein foods such as meat, fish, and dairy products. It is excreted in urine and can be used as a biomarker for exposure to phenylalanine. Elevated levels of 2-Hydroxy Hippuric Acid have been associated with liver and kidney damage, as well as certain types of cancer.
The stable isotope-labeled derivative, 2-Hydroxy Hippuric Acid-13C2,15N, is chemically identical to the non-labeled compound, except for the presence of two carbon-13 atoms and one nitrogen-15 atom. These isotopes do not significantly alter the chemical properties of the compound, but they do allow for accurate and precise quantification of 2-Hydroxy Hippuric Acid levels in biological samples.
Overall, the usage of 2-Hydroxy Hippuric Acid-13C2,15N is an important tool in metabolomics research, as it allows for the accurate and precise quantification of 2-Hydroxy Hippuric Acid levels in biological samples, which can provide valuable insights into the physiological processes and potential health risks associated with exposure to phenylalanine.
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