9-(4’-Hydroxyaminophenyl)-9H-pyrido[3,4-b]indole-d4

9-(4’-Hydroxyaminophenyl)-9H-pyrido[3,4-b]indole-d4 is a deuterated derivative of 9-(4’-Hydroxyaminophenyl)-9H-pyrido[3,4-b]indole, which is a potent and selective inhibitor of the protein kinase CK2. CK2 is involved in various biological processes, including cell proliferation, apoptosis, and DNA repair. Therefore, the inhibition of CK2 has significant therapeutic potential in the treatment of cancer and other diseases. The deuterated form of the compound, 9-(4’-Hydroxyaminophenyl)-9H-pyrido[3,4-b]indole-d4, is commonly used in pharmacokinetic studies to track the distribution, metabolism, and excretion of the parent compound in vivo. The incorporation of deuterium in the molecule enhances the sensitivity and accuracy of analytical techniques such as mass spectrometry, which are used to measure drug concentrations in biological samples. The chemical structure of 9-(4’-Hydroxyaminophenyl)-9H-pyrido[3,4-b]indole-d4 contains a pyridine ring fused with an indole moiety, with a hydroxyamine group and a deuterated phenyl group attached to the pyridine ring. The compound has a molecular weight of 311.38 g/mol and a molecular formula of C17H12D4N3O. In conclusion, 9-(4’-Hydroxyaminophenyl)-9H-pyrido[3,4-b]indole-d4 is a deuterated derivative of a potent CK2 inhibitor used in pharmacokinetic studies. Its chemical structure and properties make it a valuable tool in drug discovery and development.