9-Hydroxy Benzopyrene-d11

9-Hydroxy Benzopyrene-d11 is a labeled version of 9-hydroxybenzo[a]pyrene, which is a polycyclic aromatic hydrocarbon (PAH) that is formed during the incomplete combustion of organic matter. It is a potent carcinogen and mutagen that has been found to cause DNA damage and lead to the development of various cancers, including lung, skin, and bladder cancer. The labeled version, 9-Hydroxy Benzopyrene-d11, is used in various research studies to investigate the metabolism, distribution, and elimination of the parent compound in biological systems. Its unique labeling allows for the tracking and quantification of the compound in complex biological matrices, such as blood, urine, and tissues. Chemically, 9-Hydroxy Benzopyrene-d11 has the same structure as 9-hydroxybenzo[a]pyrene, with the exception of the deuterium atoms that are incorporated into the molecule. It has a molecular weight of 329.39 g/mol and a melting point of 217-220 °C. The compound is soluble in organic solvents such as methanol, ethanol, and dichloromethane. In summary, 9-Hydroxy Benzopyrene-d11 is a useful tool for researchers investigating the metabolism and distribution of the carcinogenic parent compound, 9-hydroxybenzo[a]pyrene. Its unique labeling allows for accurate tracking and quantification in biological systems, providing valuable insight into the toxicological effects of PAH exposure.