1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-d5 Hydrochloride

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-d5 Hydrochloride (MPTP-d5 HCl) is a deuterated form of MPTP, a chemical that is commonly used in research as a neurotoxin to induce Parkinson's disease in animal models. MPTP-d5 HCl is a labeled form of MPTP, which means that it has been modified by the addition of deuterium atoms to its structure, making it useful for tracing the fate and metabolism of MPTP in biological systems. MPTP-d5 HCl is typically used in studies that aim to understand the mechanisms of Parkinson's disease and to develop new treatments for the disease. It is commonly administered to animal models, such as mice or rats, to induce the symptoms of Parkinson's disease, including tremors, rigidity, and difficulty with movement. Researchers can then evaluate the effectiveness of new treatments or therapies for the disease by observing their effects on the animals. In terms of its chemical properties, MPTP-d5 HCl is a white or off-white crystalline powder that is soluble in water. Its chemical formula is C12H14D5N.HCl, and it has a molecular weight of 221.73 g/mol. MPTP-d5 HCl is a highly reactive compound that can undergo rapid oxidation to form toxic metabolites, which is why it is commonly used as a neurotoxin in research. Proper handling and storage of MPTP-d5 HCl is essential to ensure its safety and effectiveness in research applications.