10-Methyl Docetaxel-D3
| Product Name | 10-Methyl Docetaxel-D3 |
|---|---|
| Alternate Names | Docetaxel Stable Isotopes, Stable Isotopes of Docetaxel |
| CAT No. | CS-T-82088 |
| CAS No. | 1383561-32-7 |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Docetaxel |
| Smileys | CC(C)(C)OC(N[C@H]([C@@H](O)C(O[C@@H]1C(C)=C(C2(C)C)[C@@H](OC([2H])([2H])[2H])C([C@@]3(C)[C@@]([C@H](OC(C4=CC=CC=C4)=O)[C@]2(O)C1)([H])[C@]5(OC(C)=O)CO[C@]5([H])C[C@@H]3O)=O)=O)C6=CC=CC=C6)=O |
| Canonical Smiles | CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)OC |
| InchIKey | KWXAADKMZIJIMH-HXAYTVANSA-N |
| Inchl | InChI=1S/C44H55NO14/c1-23-27(56-38(51)32(48)31(25-16-12-10-13-17-25)45-39(52)59-40(3,4)5)21-44(53)36(57-37(50)26-18-14-11-15-19-26)34-42(8,35(49)33(54-9)30(23)41(44,6)7)28(47)20-29-43(34,22-55-29)58-24(2)46/h10-19,27-29,31-34,36,47-48,53H,20-22H2,1-9H3,(H,45,52)/t27-,28-,29+,31-,32+,33+,34-,36-,42+,43-,44+/m0/s1/i9D3 |
| IUPAC | [(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1,9-dihydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-12-(trideuteriomethoxy)-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
10-Methyl Docetaxel-D3 is a chemical compound that is primarily used as an antineoplastic agent. It is a derivative of docetaxel, which is a widely used anticancer drug. The compound is labeled with three deuterium atoms in order to facilitate its use in pharmacokinetic and pharmacodynamic studies.
The chemical formula of 10-Methyl Docetaxel-D3 is C47H51D3NO14, and its molecular weight is 894.06 g/mol. The compound is a white to off-white powder that is soluble in organic solvents such as methanol, ethanol, and DMSO.
10-Methyl Docetaxel-D3 works by inhibiting the growth of cancer cells by disrupting their microtubule network. It binds to the beta-tubulin subunit of the microtubules and prevents their depolymerization, leading to cell cycle arrest and apoptosis. The compound has been shown to be effective against a wide range of cancer types, including breast, lung, prostate, and ovarian cancer.
The recommended dosage of 10-Methyl Docetaxel-D3 varies depending on the type and stage of cancer being treated. It is usually administered intravenously over a period of several hours, and the treatment cycle may be repeated every three to four weeks. The compound may cause side effects such as fatigue, nausea, hair loss, and neuropathy, but these are usually manageable with supportive care.
In conclusion, 10-Methyl Docetaxel-D3 is a potent antineoplastic agent that is widely used in cancer treatment. Its chemical properties and mechanism of action make it an effective tool for researchers studying the pharmacokinetics and pharmacodynamics of anticancer drugs.
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Related Compounds
Docetaxel-d6 Metabolites M1 and M3 (Mixture of Diastereomers) | Hexanoyl Docetaxel Metabolites M1 and M3-d6 (Mixture of Diastereomers) | Docetaxel D9 |