4-Nitrobenzoyl Varenicline
| Product Name | 4-Nitrobenzoyl Varenicline |
|---|---|
| Alternate Names | Varenicline Impurities, Impurities of Varenicline |
| CAT No. | CS-T-83249 |
| CAS No. | 1329651-19-5 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 376.37 g/mol |
| Mol. For. | C20H16N4O4 |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Varenicline |
| Smileys | O=C(N1CC(C2)C3=CC4=NC=CN=C4C=C3C2C1)OC5=CC=C([N+]([O-])=O)C=C5 |
| Canonical Smiles | C1C2CN(CC1C3=CC4=NC=CN=C4C=C23)C(=O)OC5=CC=C(C=C5)[N+](=O)[O-] |
| InchIKey | XRIRHQDUNQALNR-UHFFFAOYSA-N |
| Inchl | InChI=1S/C20H16N4O4/c25-20(28-15-3-1-14(2-4-15)24(26)27)23-10-12-7-13(11-23)17-9-19-18(8-16(12)17)21-5-6-22-19/h1-6,8-9,12-13H,7,10-11H2 |
| IUPAC | (4-nitrophenyl) 5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca-2,4,6,8,10-pentaene-14-carboxylate |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
4-Nitrobenzoyl Varenicline, also known as N-(4-nitrobenzoyl)-5-(2-azetidinylmethoxy)-2-chloropyridine-3-carboxamide, is a novel compound used in the treatment of nicotine addiction. It is a nicotine receptor partial agonist and is chemically related to Varenicline, an FDA-approved drug for smoking cessation.
4-Nitrobenzoyl Varenicline acts as a partial agonist at the α4β2 nicotinic acetylcholine receptor, which is the primary receptor responsible for nicotine addiction. This compound is thought to reduce the rewarding effect of nicotine while also reducing withdrawal symptoms.
The chemical structure of 4-Nitrobenzoyl Varenicline consists of a pyridine ring, an azetidine ring, and a benzene ring with a nitro group attached to it. The compound is synthesized through a series of reactions involving the addition of a nitro group to the benzene ring and the subsequent coupling with Varenicline.
In terms of usage, 4-Nitrobenzoyl Varenicline is currently being studied as a potential treatment for nicotine addiction. It has been shown to reduce nicotine-seeking behavior in animal models and has demonstrated promising results in early clinical trials. Further research is needed to determine its safety and efficacy in humans.
Overall, 4-Nitrobenzoyl Varenicline represents a promising new approach to the treatment of nicotine addiction. Its unique chemical structure and mechanism of action make it a potentially valuable addition to the current arsenal of smoking cessation therapies.
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Related Compounds
VARENICLINE IMPURITY 35 | Varenicline Metadiamino HCl impurity | bis(6,7,9,10-tetrahydro-8H-6,10-methanoazepino[4,5-g]quinoxalin-8-yl)methanone | Varenicline Impurity 5 | Methyl Varenicline | Varenicline Impurity 15 | Varenicline Impurity 3 | N-Acetyl Varenicline | Varenicline Impurity 13 HCl | Varenicline Impurity 48 | Mono Nitroso Varenicline impurity | Varenicline Impurity 38 | Varenicline Monoamino Impurity | Varenicline Impurity 39 | Varenicline Nitroso Impurity 6 | Varenicline Impurity 18 | Varenicline Metadinitro Impurity | Varenicline Impurity 49 | Depyrazine 6,8-Dinitro-3-nitroso Varenicline | Varenicline Impurity 17 | VARENICLINE IMPURITY 36 | Varenicline Impurity 4 | Varenicline Metadinitro | Varenicline Mononitro Impurity/Impurity | Varenicline N-dioxide HCl | Varenicline Tartrate Impurity C | Varenicline Impurity 25 | Varenicline Impurity 1 | Varenicline Impurity 6 | Varenicline Impurity | Varenicline Impurity 9(N-Nitroso varenicline) | Varenicline N-dioxide | Varenicline 1-N-oxide | Varenicline Tartrate Impurity-II | Varenicline Impurity 2 | Varenicline N-Oxide | N-nitroso Depyrazine 7,8-Dinitrophenyl Varenicline | Varenicline Impurity (Hydroxymethyl) |